John M. Risley
John M. Risley
Professor, Biochemistry
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Contact Me

Office: Burson 236
Phone: 704-687-4844
Email: jmrisley@uncc.edu

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  • Department of Chemistry

Publications

  1. J. M. Risley and R. L. Van Etten (1990) “Assignment of Oligosaccharide Structures to Specific Sites on Human Prostatic Acid Phosphatase” J. Protein Chem. 9, 366-367.
  2. J. M. Risley (1991) “Investigations Utilizing the 18O Isotope Shift in 13C Nuclear Magnetic Resonance Spectroscopy.  1.  Correlation with 17O NMR Chemical Shifts” Magn. Reson. Chem. 29, 143-147.
  3. W. Arias and J. M. Risley (1991) “Investigations Utilizing the 18O Isotope Shift in 13C Nuclear Magnetic Resonance Spectroscopy.  2.  Observation of a Downfield Isotope Shift in 2,6-Dimethyl-4-pyrone” J. Org. Chem. 56, 3741-3744.
  4. J. M. Risley (1991) “Preparing Solutions in the Biochemistry Lab.  An Essential, Basic Skill” J. Chem. Educ. 68, 1054-1055.
  5. J. R. Rasmussen, J. Davis, J. M. Risley, and R. L. Van Etten (1992) “Identification and Derivatization of (Oligosaccharyl)amines Obtained by Treatment of Asparagine-Linked Glycopeptides with N-GLYCANASE Enzyme” J. Am. Chem. Soc. 114, 1124-1126.
  6. J. M. Risley (1996) “An Organoleptic Laboratory Experiment” J. Chem. Educ. 73, 1181-1183.
  7. L. J. Hasbrouck, C.M. Carlin, and J. M. Risley (1997) “Origin of the oxygen in the oxidation of triphenylphosphine by potassium perphosphate” Inorg. Chim. Acta 258, 123-125.
  8. L. J. Hasbrouck and J. M. Risley (1998) “Investigations Utilizing the 18O Isotope Shift in 13C Nuclear Magnetic Resonance Spectroscopy. 3. Observation of a Solvent Dependence for tert-Butyl Alcohol” Tetrahedron Lett. 39, 4191-4194.
  9. D. H. Huang and J. M. Risley (2000) “Synthesis of N4-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-L-asparagine analogues:  Succinamide, L-2-hydroxysuccinamide, and L-2-hydroxysuccinamic acid hydrazide analogues” Carbohydr. Res. 329, 487-493.
  10. 32a. D. H. Huang and J. M. Risley (2001) Corrigendum to “Synthesis of N4-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-L-asparagine analogues:  Succinamide, L-2-hydroxysuccinamide, and L-2 hydroxysuccinamic acid hydrazide analogues” Carbohydr.Res. 331, 225.
  11. Y.-Q. Xia and J. M. Risley (2001) “Synthesis of N4-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-L-Asparagine Analogues. L-2-Chloro-, L-2-Bromo-, and D,L-2-Methylsuccinamic Acid Analogues” J. Carbohydr. Chem. 20, 45-55.
  12. J. J. Malik and J. M. Risley (2001) “Synthesis of N4-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-L-asparagine analogues.  Complete NMR assignments of chloroacetamide, bromoacetamide and glycinamide analogues” Magn. Reson. Chem. 39, 98-100.  DOI: 10.1002/1097-458X(200102)39:2<101::AID-MRC797>3.0.CO;2-F
  13. J. J. Kaylor and J. M. Risley (2001) “Synthesis of N4-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-L-asparagine analogues:  n-Butyramide, 3-chloropropionamide, 3-aminopropionamide, and isovaleramide analogues” Carbohydr. Res. 331, 439-444.
  14. J. M. Risley, D. H. Huang, J. J. Kaylor, J. J. Malik, and Y.-Q. Xia (2001) “Glycosylasparaginase Inhibition Studies:  Competitive Inhibitors, Transition State Mimics, Noncompetitive Inhibitors” J. Enzyme Inhib. 16, 269-274.
  15. J. M. Risley, D. H. Huang, J. J. Kaylor, J. J. Malik, Y.-Q. Xia, and W. M. York (2001) “Glycosylasparaginase Activity Requires the a-Carboxyl Group, But Not the a-Amino Group, on N4-(2-Acetamido-2-Deoxy-b-D-Glucopyranosyl)-L-Asparagine”Arch. Biochem. Biophys. 391, 165-170.  DOI: 10.1006/abbi.2001.2416
  16. J. M. Risley (2002) “Cholesterol Biosynthesis:  Lanosterol to Cholesterol” J. Chem. Educ. 79, 377-384.
  17. W. Du and J. M. Risley (2003) “Acylation is rate-limiting in glycosylasparaginase-catalyzed hydrolysis of N4-(4´-substituted phenyl)-L-asparagines” Org. Biomol. Chem. 1, 1900-1905.  DOI: 10.1039/b301513k
  18. J. M. Risley (2007) “Reworking Exams To Teach Chemistry Content and Reinforce Student Learning” J. Chem. Educ. 84, 1445-1447.
  19. J. M. Risley (2007) “Structures for the ABO(H) Blood Group: Which Textbook is Correct?” J. Chem. Educ. 84, 1546-1547.
  20. J. M. Risley, J. P. Kastanis, and A. M. Young (2011) “Determination of the Second-Order 1H NMR Parameters for the Aromatic Protons in 4-Fluoroaniline and Application to the Analysis of the 1H NMR Spectra for the Aromatic Protons in N4-(4′-Fluorophenyl)succinamic Acid and in N4-(4′-Fluorophenyl-3,3-difluorosuccinamic Acid” J. Fluorine Chem. 132, 269-275.  DOI: 10.1016/j.jfluchem.2011.02.003 
  21. L. E. Burnham, K. J. Gano, A. M. Young, J. M. Risley, and D. S. Jones (2012) “N-(4-Isocyanophenyl)succinamic acid” Acta Cryst. E68, o2078.  DOI: 10.1107/S1600536812025226
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