{"id":97,"date":"2023-07-14T13:50:32","date_gmt":"2023-07-14T17:50:32","guid":{"rendered":"https:\/\/pages.charlotte.edu\/augustolab\/?page_id=97"},"modified":"2023-07-19T10:50:12","modified_gmt":"2023-07-19T14:50:12","slug":"publications","status":"publish","type":"page","link":"https:\/\/pages.charlotte.edu\/augustolab\/publications\/","title":{"rendered":"Selected Publications"},"content":{"rendered":"\n

Augusto<\/strong> DG <\/strong>et al. A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature. 2023. doi:10.1038\/s41586-023-06331-x<\/a><\/p>\n\n\n\n

Augusto DG<\/strong>, Hollenbach JA. HLA variation and antigen presentation in COVID-19 and SARS-CoV-2 infection. Curr Opin Immunol. 2022 Jun;76:102178. doi: 10.1016\/j.coi.2022.102178<\/a>. <\/p>\n\n\n\n

Sabatino JJ Jr, Mittl K, Rowles WM, McPolin K, Rajan JV, Laurie MT, Zamecnik CR, Dandekar R, Alvarenga BD, Loudermilk RP, Gerungan C, Spencer CM, Sagan SA, Augusto DG<\/strong>, Alexander JR, DeRisi JL, Hollenbach JA, Wilson MR, Zamvil SS, Bove R. Multiple sclerosis therapies differentially affect SARS-CoV-2 vaccine-induced antibody and T cell immunity and function. <\/a>JCI Insight. 2022 Feb 22;7(4). doi: 10.1172\/jci.insight.156978. <\/p>\n\n\n\n

Vargas LB, Beltrame MH, Ho B, Marin WM, Dandekar R, Montero-Mart\u00edn G, Fern\u00e1ndez-Vi\u00f1a MA, Hurtado AM, Hill KR, Tsuneto LT, Hutz MH, Salzano FM, Petzl-Erler ML, Hollenbach JA, Augusto DG<\/strong>. Remarkably Low KIR and HLA Diversity in Amerindians Reveals Signatures of Strong Purifying Selection Shaping the Centromeric KIR Region. Mol Biol Evol. 2022 Jan 7;39(1):msab298. doi: 10.1093\/molbev\/msab298<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>, de Almeida RC, Farias TDJ, Magalh\u00e3es WCS, Malheiros D, Lima-Costa MF, Barreto ML, Horta BL, Kumar V, Wittig M, Franke A, Busch H, Schmidt E, Roselino AM, Tarazona-Santos E, Boldt ABW, Petzl-Erler ML. Unsuspected Associations of Variants within the Genes NOTCH4 and STEAP2-AS1 Uncovered by a GWAS in Endemic Pemphigus Foliaceus. J Invest Dermatol. 2021 Nov;141(11):2741-2744. doi: 10.1016\/j.jid.2021.04.017<\/a>. <\/p>\n\n\n\n

Marin WM, Dandekar R, Augusto DG<\/strong>, Yusufali T, Heyn B, Hofmann J, Lange V, Sauter J, Norman PJ, Hollenbach JA. High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING. PLoS Comput Biol. 2021 Aug 2;17(8):e1008904. doi: 10.1371\/journal.pcbi.1008904<\/a>. <\/p>\n\n\n\n

Amorim LM, Augusto DG<\/strong>, Nemat-Gorgani N, Montero-Martin G, Marin WM, Shams H, Dandekar R, Caillier S, Parham P, Fern\u00e1ndez-Vi\u00f1a MA, Oksenberg JR, Norman PJ, Hollenbach JA. High-Resolution Characterization of KIR<\/em> Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity. Front Immunol. 2021 May 7;12:674778. doi: 10.3389\/fimmu.2021.674778<\/a>. <\/p>\n\n\n\n

Calonga-Sol\u00eds V<\/span>, Amorim LM, Farias TDJ, Petzl-Erler ML, Malheiros D, Augusto DG<\/strong>. Variation in genes implicated in B-cell development and antibody production affects susceptibility to pemphigus. Immunology. 2021 Jan;162(1):58-67. doi: 10.1111\/imm.13259<\/a>. <\/p>\n\n\n\n

Anderson KM, Augusto DG<\/strong>, Dandekar R, Shams H, Zhao C, Yusufali T, Montero-Mart\u00edn G, Marin WM, Nemat-Gorgani N, Creary LE, Caillier S, Mofrad MRK, Parham P, Fern\u00e1ndez-Vi\u00f1a M, Oksenberg JR, Norman PJ, Hollenbach JA. Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease. J Immunol. 2020 Sep 1;205(5):1323-1330. doi: 10.4049\/jimmunol.2000144.<\/a> <\/p>\n\n\n\n

Vargas LB, Dourado RM, Amorim LM, Ho B, Calonga-Sol\u00eds V<\/span>, Issler HC, Marin WM, Beltrame MH, Petzl-Erler ML, Hollenbach JA, Augusto DG<\/strong>. Single Nucleotide Polymorphism in KIR2DL1<\/em> Is Associated With HLA-C Expression in Global Populations. Front Immunol. 2020 Aug 21;11:1881. doi: 10.3389\/fimmu.2020.01881<\/a>. <\/p>\n\n\n\n

Auer ED, Tong HV, Amorim LM, Malheiros D, Hoan NX, Issler HC, Petzl-Erler ML, Beltrame MH, Boldt ABW, Toan NL, Song LH, Velavan TP, Augusto DG<\/strong>. Natural killer cell receptor variants and chronic hepatitis B virus infection in the Vietnamese population. Int J Infect Dis. 2020 Jul;96:541-547. doi: 10.1016\/j.ijid.2020.05.033<\/a>. <\/p>\n\n\n\n

Calonga-Sol\u00eds V<\/span>, Malheiros D, Beltrame MH, Vargas LB, Dourado RM, Issler HC, Wassem R, Petzl-Erler ML, Augusto DG<\/strong>. Unveiling the Diversity of Immunoglobulin Heavy Constant Gamma (IGHG<\/em>) Gene Segments in Brazilian Populations Reveals 28 Novel Alleles and Evidence of Gene Conversion and Natural Selection. Front Immunol. 2019 Jun 4;10:1161. doi: 10.3389\/fimmu.2019.01161<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>, Norman PJ, Dandekar R, Hollenbach JA. Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR<\/em> Region. Front Immunol. 2019 May 17;10:989. doi: 10.3389\/fimmu.2019.00989<\/a>. <\/p>\n\n\n\n

Hauer V, Risti M, Miranda BLM, da Silva JS, Cidral AL, Pozzi CM, Contieri FLC, Sadissou IA, Donadi EA, Augusto DG<\/strong>, Bicalho MDG. The association of HLA-G polymorphisms and the synergistic effect of sMICA and sHLA-G with chronic kidney disease and allograft acceptance. PLoS One. 2019 Feb 22;14(2):e0212750. doi: 10.1371\/journal.pone.0212750<\/a>. <\/p>\n\n\n\n

Castro MS, Issler HC, Gelmini GF, de Miranda BLM, Calonga-Sol\u00eds V<\/span>, Schmidt AH, Stein A, Bicalho MDG, Petzl-Erler ML, Augusto DG<\/strong>. High-resolution characterization of 12 classical and non-classical HLA loci in Southern Brazilians. HLA. 2019 Feb;93(2-3):80-88. doi: 10.1111\/tan.13488<\/a>. <\/p>\n\n\n\n

Amorim LM, Santos THS, Hollenbach JA, Norman PJ, Marin WM, Dandekar R, Ribeiro EMSF, Petzl-Erler ML, Augusto DG<\/strong>. Cost-effective and fast KIR gene-content genotyping by multiplex melting curve analysis. HLA. 2018 Dec;92(6):384-391. doi: 10.1111\/tan.13430<\/a>. <\/p>\n\n\n\n

Issler HC, Amorim LM, Petzl-Erler ML, Carvalho LD, Bezerra HD, Fagundes J\u00fanior J, Gadelha SR, Augusto DG<\/strong>. Southern Bahia, Brazil: KIR gene-content distribution in the highly admixed population from Ilh\u00e9us. Hum Immunol. 2018 Dec;79(12):823-824. doi: 10.1016\/j.humimm.2018.09.006<\/a>. <\/p>\n\n\n\n

Amorim LM, van Tong H, Hoan NX, Vargas LB, Ribeiro EMSF, Petzl-Erler ML, Boldt ABW, Toan NL, Song LH, Velavan TP, Augusto DG<\/strong>. KIR-HLA distribution in a Vietnamese population from Hanoi. Hum Immunol. 2018 Feb;79(2):93-100. doi: 10.1016\/j.humimm.2017.11.011<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>. The Impact of KIR Polymorphism on the Risk of Developing Cancer: Not as Strong as Imagined? Front Genet. 2016 Jun 28;7:121. doi: 10.3389\/fgene.2016.00121<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>, Amorim LM, Farias TD, Petzl-Erler ML. KIR and HLA genotyping of Japanese descendants from Curitiba, a city of predominantly European ancestry from Southern Brazil. Hum Immunol. 2016 Apr;77(4):336-7. doi: 10.1016\/j.humimm.2016.01.011<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>, Petzl-Erler ML. KIR and HLA under pressure: evidences of coevolution across worldwide populations. Hum Genet. 2015 Sep;134(9):929-40. doi: 10.1007\/s00439-015-1579-9<\/a>. <\/p>\n\n\n\n

Augusto DG,<\/strong> O’Connor GM, Lobo-Alves SC, Bass S, Martin MP, Carrington M, McVicar DW, Petzl-Erler ML. Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo. Eur J Immunol. 2015 Jul;45(7):2052-60. doi: 10.1002\/eji.201445324<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>, Hollenbach JA, Petzl-Erler ML. A deep look at KIR-HLA in Amerindians: comprehensive meta-analysis reveals limited diversity of KIR haplotypes. Hum Immunol. 2015 Apr;76(4):272-80. doi: 10.1016\/j.humimm.2015.01.025<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>, Piovezan BZ, Tsuneto LT, Callegari-Jacques SM, Petzl-Erler ML. KIR gene content in amerindians indicates influence of demographic factors. PLoS One. 2013;8(2):e56755. doi: 10.1371\/journal.pone.0056755<\/a>. <\/p>\n\n\n\n

Augusto DG<\/strong>, Zehnder-Alves L, Pincerati MR, Martin MP, Carrington M, Petzl-Erler ML. Diversity of the KIR gene cluster in an urban Brazilian population. Immunogenetics. 2012 Feb;64(2):143-52. doi: 10.1007\/s00251-011-0565-1<\/a>. <\/p>\n\n\n\n

Augusto DG,<\/strong> Lobo-Alves SC, Melo MF, Pereira NF, Petzl-Erler ML. Activating KIR and HLA Bw4 ligands are associated to decreased susceptibility to pemphigus foliaceus, an autoimmune blistering skin disease. PLoS One. 2012;7(7):e39991. doi: 10.1371\/journal.pone.0039991<\/a>. <\/p>\n\n\n\n

Full list of Publications<\/a><\/strong><\/p>\n\n\n\n

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<\/p>\n","protected":false},"excerpt":{"rendered":"

Augusto DG et al. A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature. 2023. doi:10.1038\/s41586-023-06331-x Augusto DG, Hollenbach JA. HLA variation and antigen presentation in COVID-19 and SARS-CoV-2 infection. Curr Opin Immunol. 2022 Jun;76:102178. doi: 10.1016\/j.coi.2022.102178. Sabatino JJ Jr, Mittl K, Rowles WM, McPolin K, Rajan JV, Laurie MT, Zamecnik CR, Dandekar […]<\/p>\n","protected":false},"author":4297,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-97","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/pages\/97","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/users\/4297"}],"replies":[{"embeddable":true,"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/comments?post=97"}],"version-history":[{"count":15,"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/pages\/97\/revisions"}],"predecessor-version":[{"id":256,"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/pages\/97\/revisions\/256"}],"wp:attachment":[{"href":"https:\/\/pages.charlotte.edu\/augustolab\/wp-json\/wp\/v2\/media?parent=97"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}