{"id":5,"date":"2012-10-25T22:04:15","date_gmt":"2012-10-25T22:04:15","guid":{"rendered":"http:\/\/pages.charlotte.edu\/template-faculty01\/?page_id=5"},"modified":"2019-06-11T15:54:04","modified_gmt":"2019-06-11T19:54:04","slug":"home","status":"publish","type":"page","link":"https:\/\/pages.charlotte.edu\/elo\/","title":{"rendered":"Eugenia Lo’s Lab"},"content":{"rendered":"

Malaria kills nearly 430,000 people a year and the vast majority of them are babies and young children in sub-Saharan Africa. Despite the many interventions in place,\u00a0malaria burden remains high especially in remote and rural areas where resources are scarce and living conditions are sub-optimal.<\/p>\n

My lab focuses on evolutionary genomics of malaria parasites Plasmodium<\/em>, host-parasite interactions, and molecular epidemiology in African countries. My team employs both field-based and lab-based approaches to address important questions of how malaria infect and spread among humans. Contact me if you would like to be on-board and make a contribution to understanding and tackling malaria!<\/p>\n

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Global epidemiology of malaria<\/h1>\n
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While countries such as China and Thailand in Southeast Asia are approaching malaria elimination, Africa is still home to 90% of malaria cases and 92% of malaria deaths. In 2016, an estimated $2.7 billion was funded for malaria control and elimination. Plasmodium falciparum<\/em> is the most prominent malaria parasite in Africa and is responsible for most malaria-related deaths globally. Other parasite species including P. vivax<\/em>, P. ovale<\/em>, and\u00a0P. malariae<\/em> are also observed in Africa, SE Asia, and South America. The fifth malaria parasite species\u00a0P. knowlesi<\/em> is only known to occur in SE Asia. Recently, P. simium<\/em> has been confirmed in Brazil that switches from a monkey reservoir to human beings causing malaria.<\/p>\n

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Projected changes in malaria incidence rates, 2000-2015, based on World Malaria Report 2015 <\/strong><\/h5>\n
(source: World Health Organization)<\/strong><\/h5>\n

Malaria life cycle<\/h1>\n
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The life cycle of Plasmodium<\/em> constitutes the human and female mosquito hosts. Watch the video below to learn the different stages.<\/p>\n