{"id":41,"date":"2012-12-11T14:42:25","date_gmt":"2012-12-11T14:42:25","guid":{"rendered":"http:\/\/pages.charlotte.edu\/jerry-troutman-research\/?page_id=41"},"modified":"2023-11-10T12:23:35","modified_gmt":"2023-11-10T17:23:35","slug":"publications","status":"publish","type":"page","link":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Troutman Group Publications<\/strong><\/p>\n

(16) Reid, A.J., Erickson, K.M., Hazel, J.M., Lukose, V., Troutman, J.M. (2023) Chemoenzymatic Preparation of a\u00a0Campylobacter jejuni<\/i> Lipid-Linked Heptasaccharide on an Azide-Linked Polyisoprenoid. <\/a>ACS Omega 8, (17), 15790-15798<\/p>\n

\"Figure<\/p>\n

(15) Scarbrough, B.A., Eade, C.R., Reid, A.J.,<\/em>, Williams, T.C. Troutman, J.M.\u00a0(<\/strong>2021)<\/strong> Lipopolysaccharide is a 4-aminoarabinose donor to exogenous polyisoprenyl phosphates through the reverse reaction of the enzyme ArnT.<\/a> ACS Omega 6(39) 25729-25741.<\/p>\n

\"\"<\/a><\/p>\n

(14) Reid, A.J.,<\/em> Jones K.J., Eade, C.R., Jorgenson, M.A., Troutman, J.M.\u00a0(2021) Tracking colanic acid repeat unit formation from stepwise biosynthesis inactivation in E. coli.<\/em>.<\/a> Biochemistry 60 (27) 2221-2230.<\/p>\n

\"\"<\/a><\/p>\n

(13) Eade, C.R., Wallen, T.W. , Gates, C.E. , Oliverio, C.L. , Scarbrough, B.A. , Reid, A.J. , Jorgenson, M.A., Young, K. D., Troutman, J.M.\u00a0(2021) Making the enterobacterial common antigen glycan and measuring its substrate sequestration.<\/a> ACS Chemical Biology 16(4)691-700.<\/p>\n

\"\"<\/a><\/p>\n

(12) Bosire, E.M., Eade, C.R., Schiltz, C.J., Reid, A.J., Troutman, J.M., Chappie, J.S., Altier, C. (2020) Diffusible signal factors act through AraC-type transcriptional regulators as chemical cues to repress virulence of enteric pathogens.<\/a> Infection and Immunity 88(10) e00226-20<\/p>\n

(11) Reid, A.J., Scarbrough, B., Williams, T.C., Gates, C.E., Eade, C.R., Troutman, J.M. (2020) General utilization of fluorescent polyisoprenoids with sugar selective phosphoglycosyltransferases.<\/a> Biochemistry (59)4<\/p>\n

\"Abstract<\/p>\n

(10) Scott, P.M., Erickson, K.M., Troutman, J.M. (2019) Identification of the functional roles of six key proteins in the biosynthesis of enterobacteriaceae colanic acid.<\/a> Biochemistry 58(13)<\/p>\n

\"Figure<\/p>\n

(9) Hurst, A.N., Scarbrough, B., Saleh, R., Hovey, J., Ari, F., Goyal, S., Chi, R.J., Troutman, J.M., Vivero-Escoto, J.L. (2019) Influence of cationic\u00a0meso<\/em>-substituted porphyrins on the antimicrobial photodynamic efficacy and cell membrane interaction in\u00a0Escherichia coli<\/em>.<\/a> Int. J. Mol. Sci. 20(1)<\/p>\n

(8) MacCain, W.J., Kannan S., Jameel, D.Z., Troutman. J.M., Young, K.D. (2018) A defective undecaprenyl pyrophosphate synthase induces growth and morphological defects that are suppressed by mutations in the isoprenoid pathway of Escherichia coli<\/em>.<\/a><\/span> J. Bacteriology 200(18)<\/p>\n

(7) Sharma, S., Erickson, K.M., Troutman, J.M. (2017) Complete Tetrasaccharide Repeat Unit Biosynthesis of the Immunomodulatory\u00a0Bacteroides fragilis<\/em> Capsular Polysaccharide A.<\/a><\/span> ACS Chemical Biology 12, 92-101<\/p>\n

<\/p>\n

(6) Troutman, J.M., Erickson, K.M., Scott, P.M., Hazel, J.M., Martinez, C.D., Dodbele, S. (2015) Tuning the Production of Variable Length, Fluorescent Polyisoprenoids Using Surfactant-Controlled Enzymatic Synthesis.<\/a><\/span> Biochemistry 54, 2817-27.<\/p>\n

<\/p>\n

(5) Dodbele, S., Martinez, C.D., Troutman, J.M. (2014) Species differences in alternative substrate utilization by the anti-bacterial target Undecaprenyl Pyrophosphate Synthase.<\/a><\/span> Biochemistry 53, 5042-50.
\n\"bi-2014-00545g_0008\"<\/a>(4) Troutman, J.M., Sharma, S., Erickson, K.M., Martinez, C.D. (2014) Functional Identification of a galactosyltransferase critical to Bacteroides fragilis Capsular Polysaccharide A biosynthesis.<\/a><\/span> Carbohydrate Research, 395, 19-28.<\/p>\n

\"1-s2.0-S0008621514002419-fx1\"<\/a>(3) Mostafavi, A.Z., Lujan, D.K., Erickson, K.M., Martinez, C.D., Troutman, J.M. (2013) Fluorescent probes for investigation of isoprenoid configuration and size discrimination by bactoprenol-utilizing enzymes. <\/a><\/span>Bioorg Med Chem, 21, 5428-35.<\/p>\n

\"1-s2.0-S0968089613005385-fx1\"<\/a>(2) Mostafavi, A.Z., Troutman, J.M. (2013) Biosynthetic assembly of the\u00a0Bacteroides fragilis\u00a0<\/em>capsular polysaccharide A precursor bactoprenyl diphosphate-linked acetamido-4-amino-6-deoxy galactopyranose.<\/a><\/span> Biochemistry, 53, 1939-1949.<\/p>\n

\"bi-2013-00126w_0012\"<\/a>(1) Lujan, D.K., Stanziale, J.A., Mostafavi, A.Z., Sharma, S. Troutman, J.M. (2012) Chemoenzymatic synthesis of an isoprenoid phosphate tool for the analysis of complex bacterial oligosaccharide biosynthesis.<\/a><\/span>Carbohydrate Research 359, 44-53.<\/p>\n

\"1-s2.0-S0008621512002741-fx1\"<\/a><\/p>\n

Troutman Graduate and Post-Doc Publications<\/strong><\/p>\n

(12) Subramanian, T., Pais, J.E., Liu, S., Troutman J.M., Subramanian, K.L., Fierke, C.A., Spielmann, H.P. (2012)Farnesyl diphosphate analogues with aryl moieties are efficient alternative substrates for protein farnesyltransferase.<\/a><\/span>Biochemistry 51, 8307-19.<\/p>\n

(11) Morrison, J.P., Troutman, J.M., Imperiali B. (2010)\u00a0Development of a multicomponent kinetic assay of the early enzymes in the Campylobacter jejuni N-linked glycosylation pathway.<\/a>\u00a0Bioorg Med Chem 18, 8167-71.<\/p>\n

(10) Adams, V.R., Deremer, D.L., Stevich, B., Mattingly, C.A., Gallt, B., Subramanian, T., Troutman, J.M., Spielmann, H.P. (2010)\u00a0Anticancer activity of novel unnatural synthetic isoprenoids.<\/a>\u00a0Anticancer Research 30, 2505-12.<\/p>\n

(9)Troutman, J.M., Imperiali, B.\u00a0(2009)\u00a0Campylobacter jejuni PglH is a Single Active Site Processive Polymerase that Utilizes Product Inhibition to Limit Sequential Glycosyl Transfer Reactions.<\/a>\u00a0Biochemistry 48, 2807-2816.<\/p>\n

(8)\u00a0Subramanian, T., Liu, S.,\u00a0Troutman, J.M., Andres, D.A., Spielmann H.P.\u00a0(2008)\u00a0Protein farnesyltransferase catalyzed isoprenoid transfer to peptide depends on lipid size and shape not hydrophobicity.<\/a>\u00a0Chembiochem 9, 2872-82.<\/p>\n

(7) Troutman, J. M., Subramanian, T., Andres, D. A., and Spielmann, H. P.\u00a0(2007)\u00a0Selective modification of CaaX peptides with ortho-substituted anilinogeranyl lipids by protein farnesyl transferase: competitive substrates and potent inhibitors from a library of farnesyl diphosphate analogues.\u00a0<\/a>Biochemistry 46, 11310-21.<\/p>\n

(6) Troutman, J. M., Andres, D. A., and Spielmann, H. P.\u00a0(2007)\u00a0Protein farnesyl transferase target selectivity is dependent upon peptide stimulated product release.<\/a>\u00a0Biochemistry 46, 11299-309.<\/p>\n

(5)\u00a0Roberts, M. J.,\u00a0Troutman, J. M., Chehade, K. A., Cha, H. C., Kao, J. P., Huang, X., Zhan, C. G., Peterson, Y. K., Subramanian, T., Kamalakkannan, S., Andres, D. A., and Spielmann, H. P.\u00a0(2006)\u00a0Hydrophilic Anilinogeranyl Diphosphate Prenyl Analogues Are Ras Function Inhibitors.<\/a>\u00a0Biochemistry 45, 15862-15872.<\/p>\n

(4)Troutman, J. M., Roberts, M. J., Andres, D. A., and Spielmann, H. P.\u00a0(2005)\u00a0Tools to analyze protein farnesylation in cells.<\/a>\u00a0Bioconjug Chem 16, 1209-17.<\/p>\n

(3)\u00a0Subramanian, T., Wang, Z.,\u00a0Troutman, J. M., Andres, D. A., and Spielmann, H. P.\u00a0(2005)\u00a0Directed library of anilinogeranyl analogues of farnesyl diphosphate via mixed solid- and solution-phase synthesis.<\/a>\u00a0Org Lett 7, 2109-12.<\/p>\n

(2)Troutman, J. M., Chehade, K. A., Kiegiel, K., Andres, D. A., and Spielmann, H. P.\u00a0(2004)\u00a0Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate.<\/a>\u00a0Bioorg Med Chem Lett 14, 4979-82.<\/p>\n

(1)\u00a0Kelly, M. A., Chellgren, B. W., Rucker, A. L.,\u00a0Troutman, J. M., Fried, M. G., Miller, A. F., and Creamer, T. P.\u00a0(2001)\u00a0Host-guest study of left-handed polyproline II helix formation.<\/a>\u00a0Biochemistry 40, 14376-83.<\/p>\n","protected":false},"excerpt":{"rendered":"

Troutman Group Publications (16) Reid, A.J., Erickson, K.M., Hazel, J.M., Lukose, V., Troutman, J.M. (2023) Chemoenzymatic Preparation of a\u00a0Campylobacter jejuni Lipid-Linked Heptasaccharide on an Azide-Linked Polyisoprenoid. ACS Omega 8, (17), 15790-15798 (15) Scarbrough, B.A., Eade, C.R., Reid, A.J.,, Williams, T.C. Troutman, J.M.\u00a0(2021) Lipopolysaccharide is a 4-aminoarabinose donor to exogenous polyisoprenyl phosphates through the reverse reaction […]<\/p>\n","protected":false},"author":103,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-41","page","type-page","status-publish","hentry"],"jetpack_shortlink":"https:\/\/wp.me\/P2WDvo-F","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/pages\/41","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/users\/103"}],"replies":[{"embeddable":true,"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/comments?post=41"}],"version-history":[{"count":48,"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/pages\/41\/revisions"}],"predecessor-version":[{"id":332,"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/pages\/41\/revisions\/332"}],"wp:attachment":[{"href":"https:\/\/pages.charlotte.edu\/jerry-troutman-research\/wp-json\/wp\/v2\/media?parent=41"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}