![\"\"](\"http:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-content\/uploads\/sites\/155\/2012\/10\/nate.jpg\" "\\"nate\\"")
<\/p>\nPhysics 1000: New Student Seminar<\/p>\n
Physics 1101: Introduction to Physics
\nPhysics 1202:\u00a0 Introduction to Physics in Medicine
\nPhysics 4110\/6202: Introduction to Biomedical Optics
\nOptics 6202\/8202: Fundamentals of Biomedical Optics<\/p>\n
<\/p>\n
Laser-tissue interactions
\nBiomedical optics
\nInfrared laser tissue ablation
\nMid-infrared optical fiber probes
\nMedical applications of high-power fiber lasers
\nOptical coherence tomography
\nInfrared laser nerve stimulation
\nMinimally invasive laser surgical applications
\nImage-guided surgical interventions<\/p>\n
Ph.D., Biomedical Engineering, Northwestern University<\/span>, Evanston, IL (1998) Professor, Department of Physics and Optical Science, University of North Carolina at Charlotte (2014 – Present)<\/p>\n Associate Professor, Department of Physics and Optical Science, University of North Carolina at Charlotte (2009 – 2014)<\/p>\n Assistant Professor, Department of Physics and Optical Science, University of North Carolina at Charlotte, (2006 \u2013 2009)<\/p>\n Adjunct Faculty, McKay Department of Urology, Carolinas Medical Center, Charlotte, NC (2014 – Present)<\/p>\n Adjunct Assistant Professor, Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD (2006 \u2013 Present)<\/p>\n Assistant Professor, Urology Department, Johns Hopkins School of Medicine, Baltimore, MD, (2000 \u2013 2006)<\/p>\n Director, Biophotonics Laboratory, Johns Hopkins Bayview Medical Center, Baltimore, MD, (2000 \u2013 2006)<\/p>\n Frank McClure Distinguished Postdoctoral Fellow, Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD (1998 \u2013 2000)<\/p>\n Postdoctoral Fellow, Institute for Advanced Science and Technology in Medicine, Applied Physics Laboratory, Johns Hopkins University, Laurel, MD (1998 \u2013 2000)<\/p>\n Gold Medal Winner, North America Region, Edmund Optics Educational Award (2022)<\/p>\n Outstanding Paper Award, Engineering in Urology Society Annual Meeting, Washington DC (2011)<\/p>\n Department of Defense Prostate Cancer Research Program New Idea Award (2008-2011)<\/p>\n Young Investigator Award, Department of Defense Prostate Cancer Research Program (2003-2006)<\/p>\n Young Investigator Award, Whitaker Biomedical Engineering Grant (2003-2006, Declined)<\/p>\n Professional Career Development Award, National Kidney Foundation of Maryland (2002-2003)<\/p>\n Frank McClure Distinguished Postdoctoral Fellowship, Johns Hopkins University (1998-2000)<\/p>\n Best Student Paper, American Society for Laser Medicine & Surgery, San Diego, CA (1998)<\/p>\n Walter P. Murphy Graduate Fellowship, Northwestern University (1995-1996)<\/p>\n United States Department of Education Graduate Fellowship, R.P.I. (1992-1993)<\/p>\n Senior Member of SPIE, the International Society for Optics and Photonics (2016 – Present)<\/p>\n Associate Editor, Lasers in Medical Science (2009 – 2014)<\/p>\n Program Committee, International Symposium on Biomedical Optics (SPIE), Urology: Diagnostics and Therapeutics Session, San Francisco, CA (2006 \u2013 Present)<\/p>\n Co-Chair, American Society of Lasers in Surgery and Medicine Annual Conference.\u00a0 Lasers in Urology Session.\u00a0 Dallas, TX (2007)<\/p>\n Editorial Board, Lasers in Surgery and Medicine (2003 \u2013 2021)<\/p>\n American Society for Laser Medicine and Surgery (July 2025 – June 2026) (PI-Fried) “Infrared laser sealing of vascular tissues using a transparent laparoscopic device”<\/p>\n National Institutes of Health (Sep 2019 – Aug 2023) (PI-Fried) “Laser sealing and cutting of vascular tissues”<\/p>\n National Institutes of Health (July 2014 – June 2018) (PI-Fried) “Minimally invasive laser treatment of female stress urinary incontinence”<\/p>\n Medtronic (May 2015 – Aug 2017) (PI-Fried) “Optical sealing & cutting of tissues: Phase 3”<\/p>\n Covidien (Oct 2010 – June 2014) (PI-Fried) “Optical-based sealing, cutting, and characterization of tissues”<\/p>\n Lockheed Martin Aculight (Jan 2012 – Aug 2013) (PI-Fried) “Medical laser efficacy testing”<\/p>\n NIH \/ USAID \/ Family Health International (Jan 2009 – Mar 2013) (PI-Fried) \u201cNoninvasive approaches to male sterilization\u201d<\/p>\n Department of Defense Prostate Cancer Research Program Idea Development Award (PC073709) (Mar 31, 2008 – Feb. 30, 2012) (PI-Fried)\u00a0“Novel optical methods for identification, imaging, and preservation of the cavernous nerves responsible for penile erections during prostate cancer surgery”<\/p>\n Carolinas Medical Center \/ UNC-Charlotte Collaborative Grant (Jan 2009 – Dec 2009) (Co-PI\u2019s: Fried \/ Irby) \u201cThulium fiber laser lithotripsy for treatment of kidney stones\u201d<\/p>\n UNC-Charlotte Faculty Research Grant (Jan 2009 – May 2010) (PI-Fried) \u201cSafer and more efficient fragmentation of kidney stones using a thulium fiber laser\u201d<\/p>\n UNC-Charlotte Wachovia Summer Stipends Program (May 15 – Aug. 15, 2008) (PI-Fried) \u201cTreatment of female stress urinary incontinence in a porcine model, in vivo, using a novel endoscopic laser probe\u201d<\/p>\n UNC-Charlotte Faculty Research Grant (Jan. 15, 2007 \u2013 May 30, 2008) (PI \u2013 Fried)\u00a0 “Novel optical imaging system for identification of the prostate nerves responsible for erectile function”<\/p>\n National Institutes of Health Phase II SBIR (Oct. 2005 \u2013 Sept. 2007) (PI \u2013 Tran)\u00a0 \u201cOxide glass fiber optimized for short pulse IR lasers\u201d<\/p>\n Johns Hopkins Fund for Medical Discovery (Sept 2004 \u2013 June 2006) Department of Defense Prostate Cancer Research Program Young Investigator Award (Feb. 2003 \u2013 Jan. 2006)<\/p>\n \u201cErbium:YAG laser incision of urethral strictures for treatment of urinary incontinence after prostate cancer surgery\u201d<\/p>\n American Society for Laser Medicine and Surgery (Oct. 2003 \u2013 Sept. 2004) National Kidney Foundation of Maryland Mini Grant (July 2002 \u2013 June 2003) National Kidney Foundation of Maryland Professional Development Award (July 2002 \u2013 June 2003) National Institutes of Health Phase I SBIR (June 2002 \u2013 March 2003) (PI \u2013 Tran)\u00a0 \u201cOxide glass fiber optimized for short pulse IR lasers\u201d<\/p>\n American Institute for Ultrasound in Medicine (June 2002 \u2013 Dec 2003) National Science Foundation (Oct. 1998 \u2013 Sept. 2001) (PI \u2013 Walsh) American Society for Laser Medicine and Surgery (June 1998 \u2013 Aug. 1998)<\/p>\n \u201cCryogen spray cooling during laser skin welding\u201d<\/p>\n Publications<\/strong> <\/p>\n 2024<\/strong><\/p>\n Saeed WM, Yoshino JK, Traynham AJ, Fried NM.\u00a0 Simultaneous sealing and bisection of porcine renal blood vessels, ex vivo, using a continuous-wave, infrared diode laser at 1470 nm.\u00a0 Lasers Med Sci<\/u>.\u00a0 39:161:1-10, 2024.<\/p>\n 2023<\/strong><\/p>\n Saeed WM, Fried NM.\u00a0 A real-time fluorescence feedback system for infrared laser sealing of blood vessels. IEEE J. Sel. Top. Quantum Electron<\/u>.\u00a0 29(4):1-7, 2023.<\/p>\n Saeed WM, O’Brien PJ, Yoshino J, Restelli AR, Traynham AJ, Fried NM.\u00a0 Comparison of quartz and sapphire optical chambers for infrared laser sealing of vascular tissues using a reciprocating, side-firing optical fiber: simulations and experiments. Lasers Surg. Med<\/u>.\u00a0 55(10):886-899, 2023.<\/p>\n 2022<\/strong><\/p>\n Giglio NC, Grose HM, Fried NM. Comparison of fiber optic linear beam shaping designs for laparoscopic laser sealing of vascular tissues. Opt. Eng.<\/u>\u00a0 61(2):026112, 2022.<\/p>\n Giglio NC, Fried NM. Nondestructive optical feedback systems for use during infrared laser sealing of blood vessels.\u00a0 Lasers Surg. Med<\/u>.\u00a0 54(6):875-882, 2022.<\/p>\n 2021<\/strong><\/p>\n Giglio NC, Fried NM. Computational simulations for infrared laser sealing and cutting of blood vessels.\u00a0 IEEE J. Sel. Top. Quantum Electron<\/u>.\u00a0 27(4):1-8, 2021.<\/p>\n Giglio NC, Hutchens TC, South AA, Fried NM. Dynamic properties of surfactant enhanced laser induced vapor bubbles for lithotripsy applications.\u00a0 J. Biomed. Opt<\/u>.\u00a0 26(1):018001, 2021.<\/p>\n South AA, Giglio NC Fried NM. Simulations and testing of the mechanical properties of small core optical fibers for ureteroscopy. Opt. Eng. <\/u>60(3):036110, 2021.<\/p>\n 2020<\/strong><\/p>\n Andreeva V, Vinarov A, Yaroslavsjy I, Kovalenko A, Vybornov A, Rapoport L, Enikeev D, Sorokin N, Dymov A, Tsarichenko D, Glybochko P, Fried N, Traxer O, Altshuler G, Gapontsev V.\u00a0 Preclinical comparison of superpulse thulium fiber laser and a holmium:YAG laser for lithotripsy.\u00a0 World J Urol 38(2):497-503, 2020.<\/p>\n 2019<\/strong><\/p>\n Hardy LA, Fried NM. Comparison of first generation (1908 nm) and second generation (1940 nm) Thulium fiber lasers for ablation of kidney stones.\u00a0 Opt. Eng.<\/u> 58(9):096101, 2019.<\/p>\n Hall LA, Gonzalez DA, Fried NM. Thulium fiber laser ablation of kidney stones using an automated, vibrating fiber.\u00a0 J Biomed Opt<\/u> 24(3):038001, 2019.<\/p>\n Hardy LA, Vinnichenko V, Fried NM. High-power Holmium:YAG versus Thulium fiber laser treatment of kidney stones in dusting mode: ablation rate and fragment size studies.\u00a0 Lasers Surg Med <\/u>51(6):522-530, 2019.<\/p>\n 2018<\/strong><\/p>\n Gonzalez DA, Hardy LA, Hutchens TC, Irby PB, Fried NM. Thulium fiber laser induced vapor bubble dynamics using bare, tapered, ball, hollow steel, and muzzle brake fiber optic tips.\u00a0 Opt Eng<\/u> 57(3):036106, 2018.<\/p>\n Wilson CR, Kennedy JD, Irby PB, Fried NM. Miniature ureteroscope distal tip designs for potential use in Thulium fiber laser lithotripsy.\u00a0 J Biomed Opt<\/u> 23(7):076003, 2018.<\/p>\n Fried NM.\u00a0Recent advances in infrared laser lithotripsy. Biomed Opt Express<\/u> 9(9):4552-4568, 2018.<\/p>\n Fried NM, Irby PB. Advances in laser technology and fiber optic delivery systems for use in lithotripsy.\u00a0 Nat Rev Urol<\/u> 15(9):563-573, 2018.<\/p>\n 2017<\/strong><\/p>\n Hardy LA, Hutchens TC, Larson ER, Gonzalez DA, Chang CH, Nau WH, Fried NM. Rapid sealing of porcine renal vessels, ex vivo, using a high power, 1470-nm laser and laparoscopic prototype.\u00a0 J Biomed Opt<\/u>.\u00a0 22(5):058002, 2017.<\/p>\n Hardy LA, Kennedy JD, Wilson CR, Irby PB, Fried NM. Analysis of Thulium fiber laser induced vapor bubbles for ablation of kidney stones.\u00a0 J Biophotonics 10(10):1240-1249, 2017.<\/p>\n Hutchens TC, Gonzalez DA, Irby PB, Fried NM. Fiber optic muzzle brake tip for reducing fiber burnback and stone retropulsion during Thulium fiber laser lithotripsy.\u00a0 J Biomed Opt<\/u>\u00a0 22(1):018001, 2017.<\/p>\n Chang CH, Myers EM, Kennelly MJ, Fried NM. Optical clearing of vaginal tissues, ex vivo, for minimally invasive laser treatment of female stress urinary incontinence.\u00a0 J Biomed Opt<\/u>\u00a0 22(1):018002, 2017.<\/p>\n Hardy LA, Chang CH, Myers EM, Kennelly MJ, Fried NM. Computer simulations of thermal tissue remodeling during transvaginal and transurethral laser treatment of female stress urinary incontinence.\u00a0 Lasers Surg Med<\/u> 49(2):198-205, 2017.<\/p>\n Cilip CM, Kerr D, Latimer CA, Rosenbury SB, Giglio NC, Hutchens TC, Nau WH, Fried NM. Infrared laser sealing of porcine vascular tissues using a 1470 nm diode laser:\u00a0 preliminary in vivo studies.\u00a0 Lasers Surg Med<\/u> 49(4):366-371, 2017.<\/p>\n Hutchens TC, Gonzalez DA, Hardy LA, McLanahan CS, Fried NM. Thulium fiber laser recanalization of occluded ventricular catheters in an ex vivo tissue model.\u00a0 J Biomed Opt<\/u> 22(4):048001, 2017.<\/p>\n 2016<\/strong><\/p>\n Wilson CR, Hardy LA, Kennedy JD, Irby PB, Fried NM. Miniature ball tip optical fibers for use in Thulium fiber laser ablation of kidney stones.\u00a0 J Biomed Opt<\/u> 21(1):018003, 2016.<\/p>\n Wilson CR, Hardy LA, Irby PM, Fried NM. Microscopic analysis of laser-induced proximal fiber tip damage during Holmium:YAG and Thulium fiber laser lithotripsy.\u00a0 Opt Eng<\/u> 55(4):046102, 2016.<\/p>\n 2015<\/strong><\/p>\n Blackmon RL, Hutchens TC, Hardy LA, Wilson CR, Irby PB, Fried NM. Thulium fiber laser ablation of kidney stones using a 50-micrometer-core silica optical fiber. Optical Engineering 54(1):011004, 2015.<\/p>\n Wilson CR, Hardy LA, Irby PB, Fried NM. Collateral damage to the ureter and Nitinol stone baskets during Thulium fiber laser lithotripsy. Lasers Surg Med 47(5):403-410, 2015.<\/p>\n Wilson CR, Hutchens TC, Hardy LA, Irby PB, Fried NM. A miniaturized, 1.9-French integrated optical fiber and stone basket for use in Thulium fiber laser lithotripsy. J Endourol 29(10):1110-1114, 2015..<\/p>\n Fried NM, Burnett AL. Novel methods for mapping the cavernous nerves during radical prostatectomy. Nat Rev Urol 12(8):451-460, 2015.<\/p>\n 2014<\/strong><\/p>\n Hardy LA, Wilson CR, Irby PB, Fried NM. \u00a0Thulium fiber laser lithotripsy in an in vitro ureter model. \u00a0J Biomed Opt \u00a019(12):128001, 2014.<\/p>\n Hutchens TC, Darafsheh A, Fardad A, Antoszyk AN, Ying HS, Fried NM.\u00a0 Detachable microsphere scalpel tips for potential use in ophthalmic surgery with the Erbium:YAG laser.\u00a0 J Biomed Opt\u00a0 19(1):018003, 2014. <\/span><\/p>\n Tozburun S, Lagoda GA, Burnett AL, Fried NM.\u00a0 Infrared laser nerve stimulation as a potential diagnostic method for intra-operative identification and preservation of the prostate cavernous nerves.\u00a0 IEEE J Sel Top Quantum Electron\u00a0 20(2):7101308, 2014.<\/span><\/p>\n <\/p>\n Giglio NC, Hutchens TC, Perkins WC, Latimer C, Ward A, Nau WH, Fried NM.\u00a0 Rapid sealing and cutting of porcine blood vessels, ex vivo, using a high power, 1470-nm diode laser.\u00a0 J Biomed Opt 19(3):038002, 2014.<\/p>\n Hardy LA, Wilson CR, Irby PB, Fried NM.\u00a0 Rapid Thulium fiber laser lithotripsy at pulse rates up to 500 Hz using a stone basket.\u00a0 IEEE J Sel Top Quantum Electron. 20(5):0902604, 2014.<\/p>\n 2013<\/strong> Hutchens TC, Blackmon RL, Irby PB, Fried NM. Detachable fiber optic tips for use in Thulium fiber laser lithotripsy. J Biomed Opt 18(3):038001, 2013.<\/p>\n Cilip CM, Rosenbury SB, Giglio N, Hutchens TC, Schweinsberger GR, Kerr D, Latimer C, Nau WH, Fried NM. Infrared laser thermal fusion of blood vessels: preliminary ex vivo tissue studies. J Biomed Opt 18(5):058001, 2013.<\/p>\n Tozburun S, Hutchens TC, McClain MA, Lagoda GA, Burnett AL, Fried NM.\u00a0 Temperature\u00a0 controlled optical stimulation of the rat prostate cavernous nerves.\u00a0 J Biomed Opt\u00a0 18(6):067001, 2013.<\/p>\n Hutchens TC, Blackmon RL, Irby PB, Fried NM.\u00a0 Hollow steel tips for reducing fiber burnback during Thulium fiber laser lithotripsy.\u00a0 J Biomed Opt\u00a0 18(7):078001, 2013.<\/p>\n Tozburun S, Lagoda GA, Burnett AL, Fried NM. Continuous-wave infrared subsurface optical stimulation of the rat prostate cavernous nerves using a 1490 nm diode laser. Urology 82(4):969-973, 2013.<\/p>\n 2012<\/strong> Burks D, Rosenbury SB, Kennelly MJ, Fried NM. Selective laser vaporization of polypropylene mesh used in treatment of female stress urinary incontinence and pelvic organ prolapse: preliminary studies using a red diode laser. Lasers Surg Med 44(4):325-329, 2012.<\/p>\n Blackmon RL, Irby PB, Fried NM. Enhanced thulium fiber laser lithotripsy using micro-pulse train modulation. J Biomed Opt 17(2):028002, 2012.<\/p>\n Hutchens TC, Darafsheh A, Fardad A, Antoszyk AN, Ying HS, Astratov VN, Fried NM. Characterization of novel microsphere chain fiber optic tips for potential use in ophthalmic laser surgery. J Biomed Opt 17(6):068004, 2012.<\/p>\n Tozburun S, Lagoda GA, Burnett AL, Fried NM. Subsurface near-infrared laser stimulation of the periprostatic cavernous nerves. J Biophotonics 5(10):793-800, 2012.<\/p>\n 2011<\/strong> Schweinsberger GR, Cilip CM, Trammell SR, Cherukuri H, Fried NM. Noninvasive laser coagulation of the human vas deferens: optical and thermal simulations. Lasers Surg Med 43(5):443-449, 2011.<\/p>\n Blackmon RL, Irby PB, Fried NM. Comparison of Holmium:YAG and Thulium fiber laser lithotripsy: ablation thresholds, ablation rates, and retropulsion effects. J Biomed Opt 16(7):071403, 2011.<\/p>\n Tozburun S, Lagoda GA, Burnett AL, Fried NM. Continuous-wave laser stimulation of the rat prostate cavernous nerves using a compact and inexpensive all single mode optical fiber system. J Endourol 25(11):1727-1731, 2011.<\/p>\n Cilip CM, Pierorazio PM, Ross AE, Allaf ME, Fried NM. High-frequency ultrasound imaging of noninvasive laser coagulation of the canine vas deferens. Lasers Surg Med 43:838-842, 2011.<\/p>\n 2010<\/strong> Blackmon RL, Irby PB, Fried NM. Holmium:YAG (wavelength = 2120 nm) versus Thulium fiber (wavelength = 1908 nm) laser lithotripsy. Lasers Surg Med 42(3):232-236, 2010.<\/p>\n Tozburun S, Lagoda GA, Mayeh M, Farahi F, Burnett AL, Fried NM. A compact laparoscopic probe for optical stimulation of the prostate nerves. IEEE J Sel Top Quantum Electron 16(4):941-945, 2010.<\/p>\n Cilip CM, Ross AE, Jarow JP, Fried NM. Application of an optical clearing agent during noninvasive laser coagulation of the canine vas deferens. J Biomed Opt 15(4):048001, 2010.<\/p>\n Tozburun S, Cilip CM, Lagoda GA, Burnett AL, Fried NM. Continuous-wave infrared optical nerve stimulation for potential diagnostic applications. J Biomed Opt 15(5):055012, 2010.<\/p>\n Chitchian S, Weldon TP, Fiddy MA, Fried NM. Combined image processing algorithms for improved optical coherence tomography of the prostate nerves. J Biomed Opt 15(4):046014, 2010.<\/p>\n 2009<\/strong> Chitchian S, Fiddy MA, Fried NM. Denoising during optical coherence tomography of the prostate nerves via wavelet shrinkage using dual-tree complex wavelet transform. J Biomed Opt 14(1):014031, 2009.<\/p>\n Cilip CM, Jarow JP, Fried NM. Noninvasive laser vasectomy: preliminary ex vivo tissue studies. Lasers Surg Med 41:203-207, 2009.<\/p>\n Scott NJ, Cilip CM, Fried NM. Thulium fiber laser ablation of urinary stones through small-core optical fibers. IEEE J Sel Top Quantum Electron 15(2):435-440, 2009.<\/p>\n 2008<\/strong> Rais-Bahrami S, Levinson AW, Fried NM, Lagoda GA, Hristov A, Chuang Y, Burnett AL, Su LM. Optical coherence tomography of cavernous nerves: a step toward real-time intraoperative imaging during nerve-sparing radical prostatectomy. Urology 72(1):198-204, 2008.<\/p>\n 2007<\/strong> Scott NJ, Barton RA, Casperson AL, Tchapyjnikov A, Levin K, Tran D, Fried NM. Mid-IR germanium oxide fibers for contact erbium laser tissue ablation in endoscopic surgery. IEEE J Sel Top Quantum Electron 13(6):1709-1714, 2007.<\/p>\n Fried NM, Rais-Bahrami S, Lagoda GA, Chuang AY, Su LM, Burnett AL. Identification and imaging of the nerves responsible for erectile function in rat prostate, in vivo, using optical nerve stimulation and optical coherence tomography. IEEE J Sel Top Quantum Electron 13(6):1641-1645, 2007.<\/p>\n 2006<\/strong> Polletto TJ, Ngo AK, Tchapyjnikov A, Levin K, Tran D, Fried NM. Comparison of germanium oxide fibers with silica and sapphire fiber tips for transmission of Erbium:YAG laser radiation. Lasers Surg Med 38(8):787-791, 2006.<\/p>\n 2005<\/strong> Fried NM. High-power laser vaporization of the canine prostate using a 110-watt Thulium fiber laser at 1.91 micrometers. Lasers Surg Med 36(1):52-56, 2005.<\/p>\n Fried NM, Murray KE. High-power thulium fiber laser ablation of urological tissues at 1.94 micrometers. J Endourol 19(1):25-31, 2005.<\/p>\n Fried NM. Thulium fiber laser lithotripsy: an in vitro analysis of stone fragmentation using a modulated 110-W Thulium fiber laser at 1.94 \uf06dm. Lasers Surg Med 37(1):53-58, 2005.<\/p>\n Sharma U, Fried NM, Kang JU. All-fiber common-path optical coherence tomography: sensitivity optimization and system analysis. IEEE J Sel Top Quantum Electron 11(4):799-805, 2005.<\/p>\n 2004<\/strong> Yang Y, Chaney CA, Fried NM. Erbium:YAG laser lithotripsy using hybrid germanium \/ silica optical fibers. J Endourol 18(9):830-835, 2004.<\/p>\n Ramli R, Chung CC, Fried NM, Franco N, Hayman MH. Subsurface tissue lesions created using an Nd:YAG laser with a sapphire contact cooling probe. Lasers Surg Med 35:392-396, 2004.<\/p>\n Fried NM, Yang Y, Chaney CA, Fried D. Transmission of Q-switched Erbium:YSGG and Erbium:YAG laser radiation through germanium oxide and sapphire optical fibers at high pulse energies. Lasers Med Sci 19(3):155-160, 2004.<\/p>\n 2003<\/strong> Fried NM, Tesfaye Z, Ong AM, Rha KH, Hejazi P. Optimization of the erbium:YAG laser for precise incision of ureteral and urethral tissues: in vitro and in vivo results. Lasers Surg Med 33:108-114, 2003.<\/p>\n Ramli R, Durand D, Fried NM. Subsurface tissue lesions using an Nd:YAG laser and cryogen cooling. J Endourol 17(10):923-926, 2003.<\/p>\n 2002<\/strong> Fried NM, Roberts WW, Sinelnikov YD, Wright EJ, Solomon SB. Focused ultrasound ablation of epididymis: Thermal measurements in a canine model. Fertil Steril 78(3):609-613, 2002.<\/p>\n Roberts WW, Wright EJ, Fried NM, Nichol T, Jarrett TW, Kavoussi LR, Solomon SB. High intensity focused ultrasound ablation of the epididymis in a canine model: a potential alternative to vasectomy. J Endourol 16(8):621-625, 2002.<\/p>\n 2001<\/strong> Fried NM, Fried D. Comparison of Er:YAG and 9.6-\uf06dm TE CO2 lasers for ablation of skull tissue. Lasers Surg Med 28:335-343, 2001. (cover article)<\/p>\n Fried NM, Sinelnikov Y, Pant B, Roberts WW, Solomon SB. Noninvasive vasectomy using a focused ultrasound clip: thermal measurements and simulations. IEEE Trans Biomed Eng 48(12)1453-1459, 2001.<\/p>\n Fried NM. Potential applications of the Er:YAG laser in endourology. J Endourol 15(9):889-894, 2001.<\/p>\n 2000<\/strong> Fried NM, Walsh JT. Laser skin welding: in vivo tensile strength and wound healing results. Lasers Surg Med 27: 55-65, 2000.<\/p>\n Fried NM, Lardo AC, Berger RD, Calkins H, Halperin HR. Linear lesions in myocardium created by laser using diffusing optical fibers: in vitro and in vivo results. Lasers Surg Med 27: 295-304, 2000.<\/p>\n 1999<\/strong> Fried NM, Hung VC, Walsh JT. Laser tissue welding: laser spot size and beam profile studies. IEEE J Sel Top Quantum Electron 5(4): 1004-1012, 1999.<\/p>\n 1998<\/strong> Fried NM, Walsh JT. Dye-assisted laser skin closure with pulsed radiation: an in vitro study of weld strength and thermal damage. J Biomed Opt 3: 401-408, 1998.<\/p>\n Conference Proceedings<\/strong> 2024<\/strong><\/p>\n Saeed WM, O\u2019Brien PJ, Yoshino JK, Restelli AR, Traynham AJ, Fried NM. Quartz versus sapphire optical chambers for use in infrared laser sealing of blood vessels.\u00a0 SPIE<\/u> 12817: 1-4, 2024.<\/p>\n Saeed WM, Yoshino JK, Traynham AJ, Fried NM. Simultaneous infrared laser sealing and cutting of blood vessels.\u00a0 SPIE<\/u> 12817: 1-8, 2024.<\/p>\n 2023<\/strong><\/p>\n O\u2019Brien PJ, Saeed WM, Fried NM. A transparent quartz laparoscopic jaw design for infrared laser sealing of vascular tissues using a reciprocating, side-firing optical fiber.\u00a0 SPIE<\/u> 12355: 1-7, 2023.<\/p>\n Saeed WM, Hutchens TC, Fried NM. Comparison of two surfactants for enhancing laser-induced vapor bubble dimensions.\u00a0 SPIE<\/u> 12353: 1-5, 2023.<\/p>\n Saeed WM, Fried NM. Changes in tissue fluorescence during infrared laser sealing of blood vessels.\u00a0 SPIE<\/u> 12355: 1-5, 2023.<\/p>\n Restelli AR, Saeed WM, Fried NM. A novel flexible ureteroscope design using a saline light guide channel for combined irrigation and illumination.\u00a0 SPIE<\/u> 12353: 1-7, 2023.<\/p>\n 2022<\/strong><\/p>\n Giglio NC, Grose HM, Fried NM. Reciprocating side-firing fiber for laser sealing of blood vessels.\u00a0 SPIE<\/u> 11936:1-7, 2022.<\/p>\n Giglio NC, Fried NM. Real-time, nondestructive optical feedback systems for infrared laser sealing of blood vessels. SPIE<\/u> 11936:1-5, 2022.<\/p>\n Giglio NC, Grose HM, Fried NM. Optical coherence tomography feedback system for infrared laser sealing of blood vessels.\u00a0 SPIE<\/u> 11948:1-5, 2022.<\/p>\n 2021<\/strong><\/p>\n South AA, Giglio NC, Fried NM. Simulating manual manipulation of small optical fibers within flexible ureteroscopes for potential application in Thulium fiber laser lithotripsy.\u00a0 SPIE<\/u>. 1161908:1-8, 2021.<\/p>\n Giglio NC, South AA, Fried NM. Characterization of a prototype miniature digital ureteroscope tip for enabling office-based Thulium fiber laser lithotripsy.\u00a0 SPIE<\/u> 116190F:1-7, 2021.<\/p>\n Giglio NC, Fried NM. Sealing and bisection of blood vessels using a 1470 nm laser: optical, thermal, and tissue damage simulations.\u00a0 SPIE<\/u> 1162108:1-5, 2021.<\/p>\n 2020<\/strong><\/p>\n Giglio NC, Hutchens TC, Wilson CR, Gonzalez DA, Fried NM. Surfactant enhanced laser-induced vapor bubbles for potential use in Thulium fiber laser lithotripsy. IEEE Engineering in Medicine and Biology Conference.\u00a0 In press.<\/p>\n Hutchens TC, Giglio NC, Cilip CM, Rosenbury SB, Hardy LA, Kerr DE, Hua WH, Fried NM. Novel optical linear beam shaping designs for use in laparoscopic laser sealing of vascular tissues.\u00a0 IEEE Engineering in Medicine and Biology Conference.\u00a0 In press.<\/p>\n Giglio NC, Hutchens TC, Cilip CM, Fried NM.\u00a0 Optical coherence tomography for use in infrared laser sealing of vessels.\u00a0 IEEE International Photonics Conference.\u00a0 In press.<\/p>\n 2019<\/strong><\/p>\n Gonzalez DA, Giglio NC, Hall LA, Vinnichenko V, Fried NM. Comparison of single, dual, and staircase temporal pulse profiles for reducing stone retropulsion during Thulium fiber laser lithotripsy in an in vitro stone phantom model.\u00a0 SPIE<\/u> 108520E:1-8, 2019.<\/p>\n Hardy LA and Fried NM. Comparison of 1908 and 1940 nm wavelengths for Thulium fiber laser lithotripsy. SPIE<\/u> 108520G:1-7, 2019.<\/p>\n Hardy LA, Vinnichenko V, Fried NM. Holmium:YAG versus Thulium fiber laser dusting of calcium oxalate monohydrate stones.\u00a0 SPIE<\/u> 108520I:1-6, 2019.<\/p>\n Gonzalez DA and Fried NM. Thulium fiber laser lithotripsy using small, medium, and large muzzle brake fiber optic tips.\u00a0 SPIE<\/u> 108520K:1-9, 2019.<\/p>\n Hall LA, Gonzalez DA, and Fried NM. Thulium fiber laser stone dusting using an automated, vibrating optical fiber.\u00a0 SPIE<\/u> 108520C:1-11, 2019.<\/p>\n Hall LA, Fried NM. Optical tracking of kidney stones: preliminary studies. SPIE<\/u> 1085205:1-6, 2019.<\/p>\n 2018<\/strong><\/p>\n Gonzalez DA, Hardy LA, Hutchens TC, Irby PB, Fried NM. Thulium fiber laser induced vapor bubbles using bare, tapered, ball, hollow steel, and muzzle brake fiber optic tips.\u00a0 SPIE 1046806:1-9, 2018.<\/p>\n Chang CH, Hardy LA, Peters MG, Bastawros DA, Myers EM, Kennelly MJ, Fried NM. Optical clearing of vaginal tissues in cadavers.\u00a0 SPIE 104680K:1-5, 2018.<\/p>\n Hardy LA, Gonzalez DA, Irby PB, Fried NM. Fragmentation and dusting of large kidney stones using a compact, air-cooled, high peak power, 1940-nm, Thulium fiber laser.\u00a0 SPIE 104680O:1-5, 2018.<\/p>\n Hardy LA, Irby PB, Fried NM. Scanning electron microscopy of real and artificial kidney stones before and after Thulium fiber laser ablation in air and water.\u00a0 SPIE 104680G:1-11, 2018.<\/p>\n Chan KH, Fried NM, Fried D. Selective ablation of carious lesions using an integrated near-IR imaging system and a novel 9.3-mm CO2<\/sub>\u00a0 Proc. SPIE 104730E:1-7, 2018.<\/p>\n Chung CH, Fried NM. Laser probe with integrated contact cooling for subsurface tissue thermal remodeling.\u00a0 Southeastern Biomedical Engineering Conference, Charlotte, NC, 2018.<\/p>\n 2017<\/strong><\/p>\n Wilson CR, Kennedy JD, Irby PB, Fried NM. Anti-reflection coated optical fibers for use in Thulium fiber laser lithotripsy.\u00a0 SPIE 10038:100380D:1-6, 2017.<\/p>\n Kennedy JD, Wilson CR, Irby PB, Fried NM. Miniature ureteroscope tip designs for use in Thulium fiber laser lithotripsy.\u00a0 SPIE 10038:100380Q:1-7, 2017.<\/p>\n Wilson CR, Peller JA, Trammell SR, Irby PB, Fried NM. Novel ureteroscope illumination designs.\u00a0 SPIE 10038:100380G:1-7, 2017.<\/p>\n Hutchens TC, Gonzalez DA, Irby PB, Fried NM. Thulium fiber laser lithotripsy using a muzzle brake fiber tip.\u00a0 SPIE 10038:100380G:1-8, 2017.<\/p>\n Chang CH, Myers EM, Kennelly MJ, Fried NM. Optical clearing of vaginal tissues. Proc. SPIE 10038:100380A:1-9, 2017.<\/p>\n Hardy LA, Hutchens TC, Larson ER, Gonzalez DA, Chang CH, Nau WH, Fried NM. Laparoscopic prototype for optical sealing of renal blood vessels.\u00a0 SPIE 10038:100380V:1-7, 2017.<\/p>\n Chang CH, Hammerland J, Nau WH, Fried NM. Tissue dissection using a 1470-nm diode laser and laparoscopic prototype.\u00a0 SPIE 10066:10066V:1-5, 2017.<\/p>\n 2016<\/strong><\/p>\n Hardy LA, Kennedy JD, Wilson CR, Irby PB, Fried NM. Cavitation bubble dynamics during Thulium fiber laser lithotripsy.\u00a0 SPIE<\/u>\u00a0 9689:96891Q:1-6, 2016.<\/p>\n Wilson CR, Hardy LA, Kennedy JD, Irby PB, Fried NM. Thulium fiber laser lithotripsy using small spherical distal fiber tips.\u00a0 SPIE<\/u>\u00a0 9689:96891G:1-5, 2016.<\/p>\n Wilson CR, Hardy LA, Irby PB, Fried NM. Proximal fiber tip damage during Holmium:YAG and Thulium fiber laser ablation of kidney stones.\u00a0 SPIE<\/u>\u00a0 9689:96891Q:1-6, 2016.<\/p>\n Hardy LA, Chang CH, Myers EM, Kennelly MJ, Fried NM. Laser treatment of female stress urinary incontinence: optical, thermal, and tissue damage simulations.\u00a0 SPIE<\/u>\u00a0 9689:96891R:1-6, 2016.<\/p>\n Chang CH, Fried NM. Diffusing, side-firing, and radial delivery laser balloon catheters for creating subsurface thermal lesions in tissue.\u00a0 SPIE<\/u>\u00a0 9689:96891S:1-6, 2016<\/p>\n 2015<\/strong><\/p>\n Cilip CM, Hutchens TC, Kerr D, Latimer D, Rosenbury SB, Giglio NC, Schweinsberger GR, Perkins WC, Wilson CR, Ward A, Nau WH, Fried NM. Infrared laser sealing of porcine tissues: preliminary in vivo studies. Proc. SPIE 9303:930319:1-7, 2015.<\/p>\n Wilson CR, Hardy LA, Irby PB, Fried NM. Thulium fiber laser damage to nitinol stone baskets. Proc. SPIE 9303:93031A:1-4, 2015.<\/p>\n Kaouk GS, Perkins WC, Lagoda GA, Burnett AL, Fried NM. Optical and electrical stimulation of the rat prostate cavernous nerves: priming and fatigue studies. Proc. SPIE 9303:930318:1-6, 2015.<\/p>\n Hardy LA, Wilson CR, Irby PB, Fried NM. Kidney stone ablation times and peak saline temperatures. Proc. SPIE 9303:930310:1-6, 2015.<\/p>\n Perkins WC, Lagoda GA, Burnett AL, Fried NM. Electrical stimulation vs. pulsed and continuous-wave optical stimulation of the rat prostate cavernous nerves, in vivo. Proc. SPIE 9542:954217:1-5, 2015.<\/p>\n Hung CH, Wilson CR, Fried NM. Comparison of four lasers (lambda = 650, 808, 980, and 1075 nm) for noninvasive creation of deep subsurface lesions in tissue. Proc. SPIE 9542:95420G:1-4, 2015.<\/p>\n Wilson CR, Hardy LA, Irby PB, Fried NM. Thulium fiber laser damage to the ureter. Proc. SPIE 9542:95420C:1-5, 2015.<\/p>\n 2014<\/strong><\/p>\n Giglio NC, Hutchens TC, Perkins WC, Latimer C, Ward A, Nau WH. \u00a0Rapid infrared laser sealing of porcine renal vessels, ex vivo. \u00a0Proc. SPIE 8926:892619, 2014.<\/p>\n Blackmon RL, Hutchens TC, Hardy LA, Irby PB, Fried NM. \u00a0Characterization of a 50-um-core optical fiber for potential use in Thulium fiber laser lithotripsy. \u00a0Proc. SPIE 8926:89261F, 2014,<\/p>\n Hardy LA, Wilson CR, Irby PB, Fried NM. \u00a0Rapid vaporization of kidney stones, ex vivo, using a Thulium fiber laser at pulse rates up to 500 Hz with a stone basket. \u00a0Proc. SPIE 8926:89261H, 2014.<\/p>\n Wilson CR, Hutchens TC, Hardy LA, Irby PB, Fried NM. \u00a0An integrated fiber and stone basket device for use in Thulium fiber laser lithotripsy. \u00a0Proc. SPIE 8926:89261J, 2014.<\/p>\n Perkins WC, Lagoda GA, Burnett AL, Fried NM. \u00a0A compact, inexpensive infrared laser system for continuous-wave optical stimulation of the rat prostate cavernous nerves. Proc. SPIE 8926:89261E, 2014.<\/p>\n 2013<\/strong> Cilip CM, Rosenbury SB, Giglio N, Hutchens TC, Schweinsberger GR, Kerr D, Latimer C, Nau WH, Fried NM. Thermal sealing of blood vessels using infrared lasers. Proc. SPIE 8565:85654B:1-7, 2013.<\/p>\n Hutchens TC, Blackmon RL, Irby PB, Fried NM. Comparison of detachable and tapered fiber optic tips for Thulium fiber laser lithotripsy. Proc. SPIE 8565:85651A:1-12, 2013.<\/p>\n Tozburun S, Stahl CSD, Hutchens TC, Lagoda GA, Burnett AL, Fried NM. Subsurface optical stimulation of rat prostate cavernous nerves using a continuous wave, single mode, 1490 nm diode laser. Proc. SPIE 8565:856515:1-6, 2013.<\/p>\n Tozburun S, Lagoda GA, McClain MA, Burnett AL, Fried NM. Temperature-controlled optical stimulation of the rat prostate cavernous nerves. Proc. SPIE 8565:856516:1-6, 2013.<\/p>\n Blackmon RL, Case JR, Trammell SR, Irby PB, Fried NM. Fiber optic suctioning of urinary stone phantoms during laser lithotripsy. Proc. SPIE 8565:856518:1-6, 2013.<\/p>\n Darafsheh A, Hutchens TC, Fardad A, Antoszyk AN, Ying HS, Fried NM, Astratov VN. Contact focusing multimodal probes for potential use in ophthalmic surgery with the Erbium:YAG laser. Proc. SPIE 8567:856729:1-10, 2013.<\/p>\n 2012<\/strong> Hutchens TC, Darahsheh A, Fardad A, Antoszyk AN, Ying HS, Astratov VN, Fried NM. Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery. Proc. SPIE 8218:821803:1-8, 2012.<\/p>\n Blackmon RL, Irby PB, Fried NM. Improved thulium fiber laser vaporization of urinary stones using micro-pulse packets. Proc. SPIE 8207:82071C:1-7, 2012.<\/p>\n Tozburun S, Lagoda GA, Burnett AL, Fried NM. Subsurface optical stimulation of the rat prostate nerves using continuous-wave near-infrared laser radiation. Proc SPIE 8207:82070Y:1-6, 2012.<\/p>\n Cilip CM, Allaf ME, Fried NM. Optical coherence tomography vs. high-frequency ultrasound during noninvasive laser coagulation of the canine vas deferens. Proc. SPIE 8264:82640X:1-8, 2012.<\/p>\n Darafsheh A, Lupu A, Burand SA, Hutchens TC, Fried NM, Astratov VN. Photonic nanojet-induced modes: fundamentals and applications. Proc. SPIE 8264:82640X:1-8, 2012.<\/p>\n 2011<\/strong> Tozburun S, Lagoda GA, Burnett AL, Fried NM. Continuous-wave versus pulsed infrared laser stimulation of the rat prostate cavernous nerves. Proc. SPIE 7883:78831A:1-6, 2011.<\/p>\n Blackmon RL, Irby PB, Fried NM. Holmium:YAG (wavelength=2120 nm) versus Thulium fiber laser (wavelength=1908 nm) ablation of kidney stones: thresholds, rates, and retropulsion. Proc. SPIE 7883:788318:1-7, 2011.<\/p>\n Schweinsberger GR, Cilip CM, Trammell SR, Cherukuri H, Fried NM. Optical and thermal simulations of noninvasive laser coagulation of the human vas deferens. Proc. SPIE 7883:78831C:1-8, 2011.<\/p>\n Fried NM, Blackmon RL, Irby PB. A review of thulium fiber laser ablation of kidney stones. Proc. SPIE 7914:791402:1-10, 2011.<\/p>\n Cilip CM, Schweinsberger GR, Fried NM. Comparison of 808, 980, and 1075 nm lasers for noninvasive thermal coagulation of the canine vas deferens, ex vivo. Proc. SPIE 7883:78831B:1-6, 2011.<\/p>\n Darafsheh A, Allen KW, Fardad A, Fried NM, Antoszyk AN, Ying HS, Astratov VN. Focusing capability of integrated chains of microspheres in the limit of geometrical optics. Proc. SPIE 7913:79131A:1-7, 2011.<\/p>\n Tozburun S, Cilip CM, Lagoda GA, Burnett AL, Fried NM. Continuous-wave optical stimulation of the rat prostate nerves using an all-single-mode 1455 nm diode laser and fiber system. Proc. SPIE 7883:788352:1-6, 2011.<\/p>\n Tozburun S, Lagoda GA, Burnett AL, Farahi F, Fried NM. Fiber beam shaping for optical nerve stimulation. IEEE Photonics Society Annual Meeting (IPC11) WL6:493-494, 2011.<\/p>\n 2010<\/strong><\/p>\n Blackmon RL, Irby PB, Fried NM. Comparison of Holmium:YAG and Thulium fiber lasers for lithotripsy. Proc. SPIE 7548: 75481G:1-6, 2010.<\/p>\n Blackmon RL, Irby PB, Fried NM. A tapered distal fiber tip for laser lithotripsy. Proc. SPIE 7548: 75481F:1-7, 2010.<\/p>\n Cilip CM, Ross AE, Jarow JP, Fried NM. Use of an optical clearing agent during noninvasive laser coagulation of the canine vas deferens, ex vivo and in vivo. Proc. SPIE 7548: 75481C:1-6, 2010.<\/p>\n Cilip CM, Ross AE, Jarow JP, Fried NM. Noninvasive laser coagulation of the canine vas deferens, in vivo. Proc. SPIE 7548: 75481D:1-5, 2010.<\/p>\n Chitchian S, Fried NM. Near-IR optical properties of canine prostate tissue using oblique-incidence reflectometry. Proc. SPIE 7548: 75480Z:1-6, 2010.<\/p>\n Chitchian S, Weldon TP, Fried NM. OCT image segmentation of the prostate nerves. Proc. SPIE 7443: 74431D:1-4, 2010.<\/p>\n Tozburun S, Lagoda GA, Burnett AL, Fried NM. Gaussian versus flat-top spatial beam profiles for optical stimulation of the prostate nerves. Proc. SPIE 7548: 75484W:1-6, 2010.<\/p>\n Tozburun S, Lagoda GA, Mayeh M, Burnett AL, Farahi F, Fried NM. Incorporation of fiber optic beam shaping into a laparoscopic probe for laser stimulation of the cavernous nerves. Proc. SPIE 7548:754818:1-5, 2010.<\/p>\n Darafsheh A, Kerr MD, Allen KW, Fried NM, Antoszyk AN, Ying HS, Astratov VN. Integrated microsphere arrays: light focusing and propagation effects. Proc. SPIE 7605:76050R:1-9, 2010.<\/p>\n Chitchian S, Fried NM. An edge detection algorithm for improving optical coherence tomography images of the prostate nerves. OSA BIOMED. 2010.<\/p>\n Astratov VN, Darafsheh A, Kerr MD, Allen KW, Fried NM. Focusing microprobes based on integrated chains of microspheres. Progress in Electromagnetics Research Symposium (PIERS). 2010.<\/p>\n 2009<\/strong> Cilip NM, Jarow JP, Fried NM. Noninvasive laser coagulation of the canine vas deferens, ex vivo. Proc. SPIE 1O:1-6, 2009.<\/p>\n Tozburun S, Fried NM. Design of a compact laparoscopic probe for optical stimulation of the cavernous nerves. Proc. SPIE 7161:13:1-4, 2009.<\/p>\n Chitchian S, Fiddy M, Fried NM. Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves. Proc. SPIE 7168:2N:1-6, 2009.<\/p>\n Chitchian S, Fiddy M, Fried NM. Denoising during optical coherence tomography of the prostate nerves via bivariate shrinkage using dual-tree complex wavelet transform. Proc. SPIE 7161:12:1-4, 2009.<\/p>\n 2008<\/strong> Scott NJ, Barton RA, Casperson AL, Tchapyjnikov A, Levin K, Tran D, Fried NM. Mid-IR germanium oxide fibers for Erbium:YAG and Erbium:YSGG contact laser tissue ablation in endourology. Proc. SPIE 6842:12:1-7, 2008.<\/p>\n Fried NM, Lagoda GA, Scott NJ, Su LM, Burnett AL. Optical stimulation of the cavernous nerves in the rat prostate. Proc. SPIE 6842:13:1-6, 2008.<\/p>\n Scott NJ, Trammell SR, Wittmann P, Behrens A, Tchapyjnikov A, Levin K, Tran D, Fried NM, Erbium:YAG laser emulsification of grade 4+ porcine and human cataracts using a germanium oxide fiber probe. OSA BIOMED. 2008.<\/p>\n Fried NM, Lagoda GA, Scott NJ, Su LM, Burnett AL. Laser stimulation of the cavernous nerves in the rat prostate, in vivo: optimization of wavelength, pulse energy, and pulse repetition rate. Conf Proc IEEE Eng Med Biol Soc 1:2777-2780, 2008.<\/p>\n Chitchian S, Fiddy M, Fried NM. Wavelet denoising during optical coherence tomography of the prostate nerves using the complex wavelet transform. Conf Proc IEEE Eng Med Biol Soc 1:3016-3019, 2008.<\/p>\n Cilip CM, Scott NJ, Trammell S, Fried NM. Noninvasive thermal coagulation of deep subsurface tissue structures using a laser probe with integrated contact cooling. Conf Proc IEEE Eng Med Biol Soc 1:3657-3660, 2008.<\/p>\n Shein P, Cilip CM, Quinto G, Behrens A, Fried NM. Selective laser suture lysis with a compact, low-cost, red diode laser. Conf Proc IEEE Eng Med Biol Soc 1:4358-4360, 2008.<\/p>\n 2007<\/strong> Polletto TJ, Ngo AK, Tchapyjnikov A, Levin K, Tran D, Fried NM. Transmission of high Er:YAG laser pulse energies through germanium oxide fibers with sapphire tips. Proc. SPIE 6424:016:1-5, 2007.<\/p>\n Munoz JA, Riemer JD, Hayes GB, Negus D, Fried NM. Er:YAG laser incision of urethral strictures: early clinical results. Proc. SPIE 64241:F:1-4, 2007.<\/p>\n Fried NM, Noguera G, Castro-Combs J, Behrens A. Variable depth thermal lesions in rabbit corneas using a tunable thulium fiber laser. Proc. SPIE 6426:131:1-6, 2007.<\/p>\n 2006<\/strong> Chung CC, Permpongkosol S, Varkarakis IM, Lima G, Franco N, Hayman MH, Nichol T, Fried NM. Laser probes for noninvasive coagulation of subsurface tissues. Proc. SPIE 607822:1-5, 2006.<\/p>\n Ngo AK, Fried NM. Delivery of Erbium:YAG laser radiation through side-firing germanium oxide fibers. Proc. SPIE 60830O:1-5, 2006.<\/p>\n 2005<\/strong> Varkarakis IM, Inagaki T, Allaf ME, Chan TY,Rogers CG, Wright EJ, Fried NM. Erbium vs. Holmium laser incision of the urethra and bladder neck. Proc. SPIE 5686:171-175, 2005.<\/p>\n Fried NM, Murray KE. High-power Thulium fiber laser ablation of the canine prostate. Proc. SPIE 5686:176-182, 2005.<\/p>\n Ramli R, Chung CC, Fried NM, Franco N, Hayman M. Nd:YAG laser irradiation in combination with contact tissue cooling for creation of subsurface thermal lesions. Proc. SPIE 5686:183-187, 2005.<\/p>\n Sharma U, Kang JU, Fried NM. Fizeau optical coherence tomography: sensitivity optimization and system analysis. CLEO 2005, CFA5, Baltimore, MD.<\/p>\n 2004<\/strong> Ramli R, Durand D, Fried NM. Deep subsurface thermal lesions in tissue using an Nd:YAG laser and cryogen spray cooling: preliminary in vitro results. Proc. SPIE 5312:112-116, 2004.<\/p>\n Chaney CA, Yang Y, Fried NM. Assembly and testing of germanium \/ silica optical fibers for flexible endoscopic delivery of erbium:YAG laser radiation. Proc. SPIE 5317:1-8, 2004.<\/p>\n Fried NM, Yang Y, Chaney C, Fried D. Transmission of free-running and q-switched Er:YSGG laser radiation through sapphire and germanium fibers. Proc. SPIE 5317:9-12, 2004.<\/p>\n Sharma U, Fried NM, Kang JU, Bush J. Optical coherence tomography based on an all-fiber autocorrelator using probe-end reflection as reference. CLEO 2004, CWJ3, San Francisco, CA.<\/p>\n 2003<\/strong> 2002<\/strong> Fried NM, Long GM. Erbium:YAG laser ablation of urethral and ureteral tissues. Proc. SPIE 4609:122-127, 2002.<\/p>\n 2000<\/strong> Fried NM, Lardo AC, Berger RD, Calkins H, Halperin HR. Linear lesions in heart tissue using diffused laser radiation. Proc. SPIE 3907:544-551, 2000.<\/p>\n 1999<\/strong> Fried NM, Choi B, Welch AJ, Walsh JT. Temperature measurements during laser skin welding. Proc. SPIE 3590:120-127, 1999.<\/p>\n Fried NM, Walsh JT. Dynamic cooling during laser skin welding. Proc. SPIE 3590:128-133, 1999.<\/p>\n 1998<\/strong> Invited Articles, Review Articles, and Book Chapters<\/strong> Fried NM. New laser treatment approaches for benign prostatic hyperplasia. Curr Urol Rep 8(1):47-52, 2007.<\/p>\n Fried NM, Munoz JA. Laser incision of urethral strictures. Biophoton Int 14(6):33-35, 2007.<\/p>\n Fried NM. Therapeutic applications of lasers in urology: an update. Expert Rev Med Dev 3(1):81-94, 2006.<\/p>\n Fried NM. Lasers in urology: What\u2019s New?, What\u2019s Next? Contemp Urol October:12-19, 2006.<\/p>\n Levin K, Tran D, Tchapijnikov A, Fried NM. Specialty fiber expands infrared laser applications. Biophoton Int 11(4):41-43, 2004. (cover article)<\/p>\n Fried NM. A physical approach to laser tissue welding. Dialogues in Pediatric Urology 21:4-6, 1998.<\/p>\n","protected":false},"excerpt":{"rendered":" Current Courses Physics 1000: New Student Seminar Physics 1101: Introduction to Physics Physics 1202:\u00a0 Introduction to Physics in Medicine Physics 4110\/6202: Introduction to Biomedical Optics Optics 6202\/8202: Fundamentals of Biomedical Optics Research Interests Laser-tissue interactions Biomedical optics Infrared laser tissue ablation Mid-infrared optical fiber probes Medical applications of high-power fiber lasers Optical coherence tomography Infrared […]<\/p>\n","protected":false},"author":694,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-5","page","type-page","status-publish","hentry"],"jetpack_shortlink":"https:\/\/wp.me\/P2THY4-5","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/pages\/5","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/users\/694"}],"replies":[{"embeddable":true,"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":69,"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":130,"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/pages\/5\/revisions\/130"}],"wp:attachment":[{"href":"https:\/\/pages.charlotte.edu\/nathaniel-fried\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nM.S., Physics, Rensselaer Polytechnic Institute<\/span>, Troy, NY (1994)
\nB. A., Physics, Swarthmore College<\/span>, Swarthmore, PA (1992)<\/p>\nProfessional Experience<\/h3>\n
Awards\/Honors<\/h3>\n
Professional Organizations<\/h3>\n
Professional Service<\/h3>\n
Research Funding<\/h3>\n
\n\u201cTunable thulium fiber laser for tissue ablation\u201d<\/p>\n
\n\u201cHybrid germanium \/ silica optical fibers for Erbium:YAG laser lithotripsy\u201d<\/p>\n
\n\u201cA micro-inkjet device for marking of surgical margins during laparoscopic surgery\u201d<\/p>\n
\n\u201cPrecise incision of ureteral strictures using an Erbium:YAG laser\u201d<\/p>\n
\n\u201cNoninvasive vasectomy using a therapeutic focused ultrasound clip\u201d<\/p>\n
\n\u201cLaser welding of tissue:\u00a0 modeling and experiments\u201d<\/p>\n
\nTotal of 99 peer-reviewed manuscripts.<\/p>\n
\nBlackmon RL, Case JR, Trammell SR, Irby PB, Fried NM. Fiber optic manipulation of urinary stone phantoms using Holmium:YAG and Thulium fiber lasers. J Biomed Opt 18(2):028001, 2013.<\/p>\n
\nCilip CM, Allaf ME, Fried NM. Application of optical coherence tomography and high-frequency ultrasound imaging during noninvasive laser vasectomy. J Biomedical Opt 17(4):046006, 2012.<\/p>\n
\nDarafsheh A, Fardad A, Fried NM, Antoszyk AN, Ying HS, Astratov VN. Contact focusing multimodal microprobes for ultraprecise laser tissue surgery. Optics Express 19(4):3440-3448, 2011.<\/p>\n
\nBlackmon RL, Irby PB, Fried NM. Thulium fiber laser lithotripsy using tapered fibers. Lasers Surg Med 42(1):45-50, 2010.<\/p>\n
\nChitchian S, Weldon TP, Fried NM. Segmentation of optical coherence tomography images for differentiation of the cavernous nerves from the prostate gland. J Biomed Opt 14(4):044033, 2009.<\/p>\n
\nFried NM, Lagoda GA, Scott NJ, Su LM, Burnett AL. Non-contact stimulation of the cavernous nerves in the rat prostate using a tunable-wavelength thulium fiber laser. J Endourol 22(3):409-413, 2008.<\/p>\n
\nFried NM, Rais-Bahrami S, Lagoda GA, Chuang Y, Burnett AL, Su LM. Imaging the cavernous nerves in rat prostate using optical coherence tomography. Lasers Surg Med 39(1):36-41, 2007.<\/p>\n
\nNgo AK, Fried NM. Side-firing germanium oxide optical fibers for use with the Erbium:YAG laser. J Endourol 20(7):475-478, 2006.<\/p>\n
\nVarkarakis IM, Inagaki T, Allaf ME, Chan TY, Rogers CG, Wright EJ, Fried NM. Comparison of Erbium:YAG and Holmium:YAG lasers for incision of the urethra and bladder neck in a chronic porcine model. Urology 65(1):191-195, 2005.<\/p>\n
\nChaney CA, Yang Y, Fried NM. Hybrid germanium \/ silica optical fibers for endoscopic delivery of erbium:YAG laser radiation. Lasers Surg Med 24:5-11, 2004.<\/p>\n
\nSolomon SB, Nicol TL, Chan DY, Fjield T, Fried NM, Kavoussi LR. Histologic evaluation of high intensity focused ultrasound in rabbit muscle. Invest Radiol 38(5):293-301, 2003.<\/p>\n
\nRoberts WW, Chan DY, Fried NM, Wright EJ, Nicol T, Jarrett TW, Kavoussi LR, Solomon SB. High intensity focused ultrasound ablation of the vas deferens in a canine model. J Urol 167:2613-2617, 2002.<\/p>\n
\nFried NM, Tsitlik A, Rent K, Berger RD, Lardo AC, Calkins H, Halperin HR. Laser ablation of the pulmonary veins using a fiberoptic balloon catheter: implications for treatment of paroxysmal atrial fibrillation. Lasers Surg Med 28:197-203, 2001. (cover article)<\/p>\n
\nFried NM, Walsh JT. Cryogen spray cooling during laser tissue welding. Physics Med Biol 45: 753-763, 2000.<\/p>\n
\nFried NM, Choi B, Welch AJ, Walsh JT. Radiometric surface temperature measurements during dye-assisted laser skin closure: in vitro and in vivo results. Lasers Surg Med 25: 291-303, 1999.<\/p>\n
\nFried NM. Dye-assisted photothermal tissue welding. Ph.D. Thesis, Northwestern University, Evanston, IL, 1998.<\/p>\n
\nTotal of 125 proceedings papers<\/p>\n
\nStahl CSD, Tozburun S, Hutchens TC, Lagoda GA, Burnett AL, Keller MD, Fried NM. Comparison of three pulsed infrared lasers for optical stimulation of the rat prostate cavernous nerves. Proc. SPIE 8565:85655N:1-5, 2013.<\/p>\n
\nBurks D, Rosenbury SB, Kennelly MJ, Fried NM. Selective laser vaporization of polypropylene sutures and mesh. Proc. SPIE 8207:820710:1-7, 2012.<\/p>\n
\nChitchian S, Lagoda GA, Burnett AL, Fried NM. Fourier-domain versus time-domain optical coherence tomography of the prostate nerves. Proc. SPIE 7883:788314:1-7, 2011.<\/p>\n
\nScott NJ, Cilip CM, Fried NM. Thulium fiber laser lithotripsy. Proc. SPIE 1E:1-7, 2009.<\/p>\n
\nCasperson AL, Barton RA, Scott NJ, Fried NM. Holmium:YAG versus Thulium fiber laser for high-power vaporization of prostate tissue. Proc. SPIE 6842:0Y:1-5, 2008.<\/p>\n
\nFried NM, Rais-Bahrami S, Lagoda GA, Chuang Y, Burnett AL, Su LM. Optical coherence tomography of the rat cavernous nerves. Proc. SPIE 6424:0W:1-8, 2007.<\/p>\n
\nNgo AK, Sharma U, Kang JU, Fried NM. Laser welding of urinary tissues using a tunable Thulium fiber laser. Proc. SPIE 60781B:1-8, 2006.<\/p>\n
\nFried NM, Yang Y, Lee K, Tafti HA. Transmission of free-running and Q-switched Er:YAG and Er:YSGG laser energy through germanium oxide \/ silica fibers. Proc. SPIE 5691:115-119, 2005.<\/p>\n
\nFried NM, Tesfaye Z, Ong AM, Rha KH, Hejazi P. Variable pulsewidth erbium:YAG laser ablation of the ureter and urethra in vitro and in vivo: optimization of the laser fluence, pulse duration, and pulse repetition rate. Proc. SPIE 5312:105-111, 2004.<\/p>\n
\nFried NM, Roberts WW, Sinelnikov YD, Wright EJ, Solomon SB. Comparison of the vas deferens and epididymis as targets for noninvasive male sterilization using focused ultrasound. 2nd International Symposium on Therapeutic Ultrasound, pp. 155-162, 2003.<\/p>\n
\nFried NM, Sinelnikov YD, Roberts WW, Solomon SB. Incisionless vasectomy using focused ultrasound. Proc. SPIE 4609:115-121, 2002.<\/p>\n
\nFried NM, Fried D. Laser ablation of skull tissue using transverse excited 9.6-\uf06dm CO2 lasers with pulse durations of 1-100 \uf06ds. Proc. SPIE 3914:128-136, 2000.<\/p>\n
\nFried NM, Hung VC, Walsh JT. Laser spot size and beam profile studies for tissue welding applications. Proc. SPIE 3590:111-119, 1999.<\/p>\n
\nFried NM, Walsh JT. Skin welding using pulsed radiation and a dye. Proc. SPIE 3245:262-267, 1998.<\/p>\n
\nFried NM, Matlaga BR. \u201cLaser\/light applications in urology\u201d, Ch. 41, In Lasers in Dermatology and Medicine, ed. Nouri K. Springer, 2011.<\/p>\n