• Eugenia Lo’s Lab
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Contact Me

Office: Woodward 381C
Phone: 704.687.8532
Email: Eugenia.Lo@uncc.edu
Twitter: https://twitter.com/UNCC_Lo_Lab

Links

  • Department Site
  • Plasmodium falciparum genetic diversity and antimalarial drug resistance prevalence across different transmission zones in Ghana
  • Population structure and diversity of Plasmodium falciparum parasites in children with asymptomatic malaria living in different ecological zones of Ghana

RSS Latest Malaria News

  • Modelling to inform next-generation medical interventions for malaria prevention and treatment
  • Exploring alternative insecticide delivery options in a “lethal house lure” for malaria vector control
  • Evaluation of a point-of-care haemozoin assay (Gazelle device) for rapid detection of Plasmodium knowlesi malaria

Eugenia Lo’s Lab

Malaria kills nearly 430,000 people a year and the vast majority of them are babies and young children in sub-Saharan Africa. Despite the many interventions in place, malaria burden remains high especially in remote and rural areas where resources are scarce and living conditions are sub-optimal.

My lab focuses on evolutionary genomics of malaria parasites Plasmodium, host-parasite interactions, and molecular epidemiology in African countries. My team employs both field-based and lab-based approaches to address important questions of how malaria infect and spread among humans. Contact me if you would like to be on-board and make a contribution to understanding and tackling malaria!

   

Global epidemiology of malaria


While countries such as China and Thailand in Southeast Asia are approaching malaria elimination, Africa is still home to 90% of malaria cases and 92% of malaria deaths. In 2016, an estimated $2.7 billion was funded for malaria control and elimination. Plasmodium falciparum is the most prominent malaria parasite in Africa and is responsible for most malaria-related deaths globally. Other parasite species including P. vivax, P. ovale, and P. malariae are also observed in Africa, SE Asia, and South America. The fifth malaria parasite species P. knowlesi is only known to occur in SE Asia. Recently, P. simium has been confirmed in Brazil that switches from a monkey reservoir to human beings causing malaria.

Projected changes in malaria incidence rates, 2000-2015, based on World Malaria Report 2015
(source: World Health Organization)

Malaria life cycle


The life cycle of Plasmodium constitutes the human and female mosquito hosts. Watch the video below to learn the different stages.

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