The Marino lab works to advance our understanding of the regulation of skeletal muscle mass and metabolism to improve sports performance. Dr. Marino is currently the Departmental Research Project Director for the U.S. Performance Center, providing access to National and Olympic-level athletes. Furthermore, Dr. Marino has established several industry partnerships focused on improving recovery and reducing stress in athletes. Our current research interests include:
- The effects of sport specialization on long-term athlete development
- Risk factors associated with the female athlete triad
- The effect of sleep disturbance on athletic performance and health
- Resistance training adaptations in healthy and diseased skeletal muscle
Education:
- B.A. (2003) Exercise Science, Adelphi University, Garden City, NY
- M.A. (2004) Exercise Science, Adelphi University, Garden City, NY
- Ph.D. (2009) Applied Physiology, University of Toledo, Toledo, OH. Area of Study: The contribution of exercise-induced inflammation to skeletal muscle hypertrophy
- Postdoctoral Training (2013) University of Toledo, College of Medicine, Center for Diabetes and Endocrine Research, Toledo, OH. Area of Study: Neuro-endocrine regulation of obesity and metabolic disease
Peer Reviewed Publications (Since 2013, *Students Under Dr. Marino’s Mentorship):
Ebony C. Gaillard EC, Jeanette M. Bennett, Joseph S. Marino, Adam M. Reitzel, Soma S. Nag, and Reuben Howden. Relative handgrip strength is associated with hypertension risk acutely, but not longitudinally in Black and White women. Translational Journal of the American College of Sports Medicine (in review)
Ebony C. Gaillard EC, Jeanette M. Bennett, Joseph S. Marino, Adam M. Reitzel, Soma S. Nag, and Reuben Howden. The association between relative handgrip strength and hypertension status in US Black and White women: 2011-2014 National Health and Nutrition Survey. NPJ Women’s Health (in review)
Joseph S. Marino, *Gabriel Asbell, and J.P. Barfield. Para Table Tennis: Implications for Health and Rehabilitation. International Journal of Sports Physiology and Performance (in review)
*Samantha Brooks, Hannah Peach, Reuben Howden, Jennifer Lowrie, Joseph S. Marino. Impact of Perfectionism on the Risk of the Female Athlete Triad in Collegiate Athletes. Journal of Strength and Conditioning Research (Online Ahead of Print)
Genesee J. Martinez, Zachary A. Kipp, Wang-Hsin Lee, Evelyn A. Bates, Andrew J. Morris, Joseph S. Marino, Terry D. Hinds Jr. Glucocorticoid resistance remodels liver lipids and prompts lipogenesis, eicosanoid, and inflammatory pathways. Prostaglandins and Other Lipid Mediators 2024, 173
Marco Beato1*, Joseph S. Marino2, and Antonio Dello Iacono3, Editorial: Debates in Elite Sports andPerformance Enhancement. Front. Sports Act. Living 2023
^Nicole L. Stott Bond, Didier Dreau, Ian Marriott, Jeanette M. Bennett, Michael J. Turner, Susan T. Arthur, and Joseph S. Marino. Low-Dose Metformin Treatment Reduces In vitro Growth of the LL/2 Non-Small Cell Lung Cancer Cell Line. Biomedicines 2023, 11, 65
Benjamin DH Gordon1 PhD, Emily W Zacherle2 MS, Sarah Whitmire2 MS, Larry J Leamy3 PhD, Jeanette M Bennett4 PhD, Joseph S Marino2 PhD, Adam M Reitzel3 PhD, Yvette Huet2 PhD, Ian L Swaine5 PhD, Daniel S Baddeley-White5 PhD, Reuben Howden2 PhD. Isometric Exercise and Blood Pressure: 12-weeks of Training/Detraining in the Elderly. JCEP 2023, 12 (1), 3-11
Nicole L. Stott Bond*, Didier Dreau, Ian Marriott, Jeanette M. Bennett, Michael J. Turner, Susan T. Arthur, and Joseph S. Marino. Low-Dose Metformin as a Monotherapy Does Not Reduce Non-Small-Cell Lung Cancer Tumor Burden in Mice. Biomedicines 2021, 9, 1685
Jeffrey C. Gerrard, Jamison P. Hay, Ryan N. Adams, James C. Williams III, Joshua R. Huot, Kaitlin M. Weathers, Joseph S. Marino, and Susan T. Arthur. Current Thoughts of Notch’s Role in Myoblast Regulation and Muscle-Associated Disease. Int. J. Environ. Res. Public Health 2021, 18, 12558
Joshua R. Huot, Brian Thompson, Charlotte McMullen, Joseph S. Marino, Susan T. Arthur. GSI treatment preserves protein synthesis in C2C12 myotubes. Cells 2021, 10, 1786
*Nicole L. Stott and Joseph S. Marino. High fat rodent models of type 2 diabetes: From rodent to human. Nutrients 2020, 12, 3650
Joshua R. Huot, Joseph S. Marino, Micheal J. Turner, and Susan T. Arthur. Notch Inhibition via GSI Treatment Elevates Protein Synthesis in C2C12 Myotubes. Biology 2020, 2; 9(6):115
Benjamin DH Gordon, Sarah Whitmire, Emily W. Zacherle, Shelton Doyle, Sanjeev Gulati, Larry J. Leamy, Joseph Marino, Jeanette Bennett, Adam Reitzel, Ian Swaine, Reuben Howden. “Get a Grip on Hypertension” Exploring the use of isometric handgrip training in cardiopulmonary rehabilitation. J Cardiopulm Rehabil and preven 2019, 39(6):E31-E34
Benjamin DH Gordon, Erin Vinoski, Jan Warren-Findlow, Joseph Marino, Jeanette Bennett; Adam Reitzel, Larry Leamy, Ian Swaine, Reuben Howden. A comparison of blood pressure reduction following 12-weeks of isometric exercise training either in the laboratory or at home. J Am Soc Hypertens 12(11) (2018) 798-808
*Bailey Peck, Josh Huot, *Tim Renzi, Susan T. Arthur, Michael J. Turner, and Joseph S. Marino. Mice Lacking PKCθ in Skeletal Muscle Have Reduced Intramyocellular Lipid Accumulation and Increased Insulin Responsiveness in Skeletal Muscle. Am J Physiology Regul Integr Comp Physiology. 2018, 1;314(3):R468-R477
Bennett, J. M., Marino, J. S., *Peck, B., Roos, L. G., Joseph, K. M., Carter, L. B., Smith, C. B., Rohleder, N. & Coffman, M. J. Smokers display reduced glucocorticoid sensitivity prior to symptomatic chronic disease development. Ann Behav Med. 2018, 13;52(10):830-841
Joseph S. Marino, Cynthiya Ruban, Bill Saunders, MPH; Christopher M. Blanchette, The association of COPD exacerbations with new onset type 2 diabetes among Medicare participants. JHEOR 2017;5(2):183-93
*Bailey Peck, *Timoty Renzi, Hannah Peach, Jane Gaultney, and Joseph S. Marino. Examination of Risk for Sleep Disordered Breathing among College Football Players. J Sport Rehabil Epub 2018, Sep29. 2019 1;28(2):126-132
Bennett, J. M., Roos, L. G., Marino, J. S., Rohleder, N., & Coffman, M. J. (2017). Healthy smokers: An oxymoron? Maybe, but it is more complicated than that. In J. P. Sturmberg (Ed) The Value of Systems and Complexity Sciences for Healthcare – Proceedings of the 2nd International Conference of Systems and Complexity in Health (pp 23-39). New York: Springer.
Joseph S. Marino, Lance A. Stechschulte, David E. Stec, Andrea Nestor-Kalinoski, Sydni Coleman, and Terry D. Hinds, Jr. Glucocorticoid receptor β induces hepatic steatosis by augmenting inflammation and inhibition of the peroxisome proliferator-activated receptor (PPAR) α. (2016) J. Biol. Chem. doi: 10.1074/jbc.M116.752311 jbc.M116.752311. *Selected as Paper of the Week, now known as Editors Pick. http://www.jbc.org/content/291/50/25776/suppl/DCAuthor_profile
Terry D. Hinds Jr., *Bailey Peck, *Evan Shek, *Steven Stroup, *Jennifer Hinson, Susan Arthur, and Joseph S Marino. Overexpression of Glucocorticoid Receptor Beta Enhances Myogenesis and Reduces Catabolic Gene Expression. Int. J. Mol. Sci. 2016, 17(2), 232; doi:10.3390/ijms17020232
Turner MJ, Guderian S, Wikstrom EA, Huot JR, *Peck BD, Arthur ST, Marino JS, Hubbard-Turner T. Altered left ventricular performance in aging physically active mice with an ankle sprain injury. Age. 2016 Feb;38(1):15. doi: 10.1007/s11357-016-9877-2.
John K, Marino JS, Sanchez ER, Hinds TD Jr. The Glucocorticoid Receptor: Cause of Cure for Obesity? Am J Physiol Endocrinol Metab. 2015 Dec 29:ajpendo.00478.2015. doi: 10.1152/ajpendo.00478.2015
Lance A. Stechschutle, Leah Wuescher, Joseph S. Marino, Jennifer W. Hill, Charis Eng, and Terry D. Hinds, Jr. Glucocorticoid Receptor β Stimulates Akt1 Growth Pathway by Attenuation of PTEN. (2014) J. Biol. Chem. Doi:10.1074/jbc.M113.544072
Abigail R. Dowling, Laura B. Nedorezov, Xiaoliang Qiu, Joseph S. Marino, Jennifer W. Hill. Genetic Factors Modulate the Impact of Pubertal Androgen Excess on Insulin Sensitivity and Fertility. (2013) PLOS One 8(11): e79849. doi:10.1371/journal.pone.0079849
Joseph S. Marino, Terry D. Hinds, Jr., *Rachael A. Hoover, *Eric Ondrus, *Jeremy L. Onion, Abigail Dowling, Thomas McLoughlin, Edwin R. Sanchez and Jennifer W. Hill. Suppression of Protein Kinase C Theta Contributes to Enhanced Myogenesis in vitro via IRS1 and ERK1/2. BMC Cell Biology 2013, 14:39
Christopher L. Dearth, Qingnian Goh, Joseph S. Marino, Peter A. Cicinelli, Maria J. Torres-Palsa, Philippe Pierre, Randall G. Worth, Francis X. Pizza. (2013) Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response. PLOS One 8(3): e58486. doi:10.1371/journal.pone.0058486
Xiaoliang Qiu, Abigail R Dowling, Joseph S Marino, Latrice D Faulkner, Jens C. Brüning, Carol F Elias, Benjamin Bryant, Jennifer W Hill. Delayed Puberty but Normal Fertility in Mice with Selective Deletion of Insulin Receptors from Kiss1 Cells. 2013. Endocrinology. March 2013, 154(3):1337-1348
- Principles of Strength and Conditioning (UG)
- Exercise Testing and Prescription (UG)
- Research Methods in Kinesiology (UG,G)
- Adv. Principles of Strength and Conditioning (G)
- Exercise Testing for Strength and Conditioning (G)
- The office of Disability Services Outstanding Faculty Award, UNC Charlotte (2013-2014)
- The College of Health and Human Services Faculty Excellence Award in Mentoring, UNC Charlotte (2016)
- The College of Health and Human Services Graduate Teaching Excellence Award, UNC Charlotte (2024)
