Associate Professor
Biochemistry
B.A.: Kalamazoo College Ph.D.: Princeton UniversityPostdoctoral: (NIH-NRSA)
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CURRENT NEWS:
Our next group meeting is scheduled for WEDNESDAY November 9, 2022 in room 210 of the New Science Building. Caroline will be leading a discussion of a hydrogel application of iMotif technologies for delivering oral Insulin.
Getting to know the Krueger Research team-Fall2022
We are a powerhouse group of primarily female graduate and undergraduate (and sometimes high school) students, each of whom harbor a passion for scientific research. We all want to learn how to properly prepare samples and buffers, collect and analyze data, and effectively communicate our results, trials and questions with one another and the larger scientific community. I hope that you find this website useful in your quest to find out about the research conducted in the Krueger Research group. Students who have the commitment and passion to join our team are invited and encouraged to stop by the laboratory to introduce yourself and/or to attend a scheduled group meeting or two. Email Dr. Krueger if you would like to join us for an upcoming meeting or to schedule a personal interview.
Current Students
Ph.D. Nanoscale Science
| Kanika Dhiman | |
 | Will be using Small angle X-ray and Neutron Scattering to study Insulin aggregation behavior. |
Master in Chemistry Students
| Caroline West | Structural Studies of Nucleic Acid Quadruplex Formation |
 | Caroline was a post-baccalaureate UG researcher who recently joined the Master’s program in Chemistry and will be working on characterizing the relationship between Lithium ions and the formation of DNA quadruplexes upstream from the serotonin uptake receptor gene. |
| Bianca Avram | Structural studies of Insulin Amyloid Fibrils |
 | Bianca is a senior BS Chemistry Honors student with a minor in Biology who plans to apply to our early entry Masters program this Spring. She is interested in studying the aggregation phenomena of Insulin using a fluorescence assay she is developing in our lab. |
BS Chemistry Undergraduate Students
| Sarah Farina | |
| Sarah is a senior BS Chemistry major graduating this Spring. She is working with Caroline West, optimizing the chemistry department’s Circular Dichroism instrument to identify nucleic acid chiral microenvironments. She is crazy creative and will help to make awesome figures for us! Now, if only we had ChemBio Draw to go with Chem Draw. |
Former Master’s Students
Jon Trullinger *12
Protein Stabilization in presence of Ionic Liquids
Jon is currently an Operations Specialist for IQVIA. Since leaving the lab he has been actively employed in the Research Triangle Area of North Carolina including BASF, TensTech, Inc. and Syngeta
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Ryan Oliver *10
Constraints for Building Structural Models of Gelsolin, an Actin Dimer, and their Complex in Solution using Small-angle Scattering Data
Ryan received his Ph.D. at the University of Virgina in the Spring of 2014. He post-docHe recently accepted a Research Scientist position at Novo Nordisk in the Copenhagen Area, Denmark where he lives along with Heather Sullivan (*10) who is passionate about cleaning up plastic rafts in our oceans and received her Ph.D in environmental science at UVA.
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Christopher Boone *09
Toward a Structural Understanding of the Viral Entry Mechanism of HIV-1
Chris received his Ph.D from the University of Florida in Gainesville in 2014. He was a Postdoctoral Research Fellow at Harvard Medical School in Boston, where he met his current wife, Ashley White. Together, they have a son, Abraham. After a second post-doc at Texas A&M University, Chris has accepted a position as a Research Scientist at Xtal BioStructures, Inc. in Natick, MA.
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Matthew Paine *06
Shape restoration modeling of SAXS data on Ca2+ titration of gelsolin
Matt earned his M.D. at the Brody School of Medicine of East Carolina University and is currently an Attending Physician at Bon Secours Richmond Health System after completing his residency at VIDANT Medical Center near Greenville, NC. He lives in Midlothian, VA with his wife, Olga Paine, whom he met while at UNC Charlotte, and their two children.
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Malgorzata Tracka *06
Following the secondary structure rearrangements with gelsolin and actin upon complex formation using Circular Dichroism and Fourier Transform Infrared Spectroscopy
Gosia has been working as a Research Scientist in local industries since leaving UNC Charlotte. Most recently, she accepted a position at Thermo Fisher Scientific in Greenville, NC. She has also worked for Polpharma Biologics in Poland, MedImmune in Cambridge, UK and Actavis (now Allergan) in Lincolnton, NC.
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Jonathan Osborne *06
Allosteric regulation of phosphodiesterase-5 by divalent cations, cGMP and Viagra; domain structure rearrangements as observed by small-angle X-ray scattering
Jon is currently a Research Associate II at Genentech in South San Franscisco. His former positions include working at Pfizer in San Franscisco and SillaJen in Korea. Immediately after leaving UNC Charlotte, He worked as a Research Technician at John Hopkins and in a muscle protein research group at the University of Maryland in Baltimore.
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Nidhi Modi *05
Investigation into the deuteration level of proteins using electrospray ionization mass spectroscopy and NMR
Nidhi began working on a PhD in Kentucky, before leaving science to raise a family.
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Paul Perryman *01
Small-angle x-ray scattering reveals Ca2+-induced activation of the actin-binding protein gelsolin
For several years after graduating from UNCC, Paul was a Science teacher at Jordan HS and then Durham school of the Arts. In 2007, he left the teaching profession to purse an Nursing degree specializing in Anesthesia at Chapel Hill. He currently works as an RN for the North Carolina Health Care System.