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Chi Lab
Chi Lab
A Membrane Trafficking and Educational Research Group
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Principal Investigator

Office: Woodward 490D
Office Phone: (704) 687-8697
Email: richard.chi@uncc.edu

Lab: Woodward 477
Lab Phone: (704) 687-5389

Mailing Address:

Dr. Richard Chi
Department of Biological Sciences
University of North Carolina at Charlotte
9201 University City Blvd
Charlotte, NC. 28223

Links

  • Department of Biological Sciences
  • Listen to Dr. Chi's JCB Biobytes

Selected Publications

2015 to Present

Grissom, J.H., Segarra, V.A., Chi, R.J. New Perspectives on SNARE Function in the Yeast Minimal Endomembrane System. Genes (Basel). 2020;11(8):E899. Published 2020 Aug 6. doi:10.3390/genes11080899

Ma, M., Goyal, S., Burd, C. G., Chi, R. J. Expression, Purification, and Liposome Binding of Budding Yeast SNX-BAR Heterodimers. J Vis Exp. 2019 Dec 6;(154). doi: 10.3791/60413. PubMed PMID: 31868175.

Goyal, S.,Robinson, M.R., Segarra, V.A., and Chi, R. J.  (October 7th 2019). Intracellular Lipid Homeostasis and Trafficking in Autophagy [Online First], IntechOpen, DOI: 10.5772/intechopen.89683. Available from: https://www.intechopen.com/online-first/intracellular-lipid-homeostasis-and-trafficking-in-autophagy

Hurst, A.N., Scarbrough, B., Saleh, R., Hovey, J., Ari, F., Goyal, S., Chi, R. J., Troutman, J,M., Vivero-Escoto, J.L. Influence of Cationic meso-Substituted Porphyrins on the Antimicrobial Photodynamic Efficacy and Cell Membrane Interaction in Escherichia coli. International Journal of Molecular Sciences. 2019; 20(1).

Ma, M., Kumar S., Purushothaman, L., Babst, M., Ungermann, C., Chi, R. J. and Burd, C. G.*, Lipid Trafficking by yeast Snx4 family of SNX-BAR proteins promotes autophagy and vacoule fusion. Molecular Biology of the Cell. 2018 (18):20190-2200.

Gaspar, T. R., Chi, R. J., Parrow, M.W., Ringwood, A. W., “Cellular Bioreactivity of Micro- and Nano- Plastic Particles in Oysters”. Frontiers in Marine Science, 2018 October 10; 5:345

Ma, M., C. G. Burd* and Chi, R. J.*,(2017). “Distinct complexes of yeast Snx4 family SNX-BARs mediate retrograde trafficking of Snc1 and Atg27.”Traffic 18(2):134-144. 

Chi, R. J., M. S. Harrison and C. G. Burd (2015). “Biogenesis of endosome-derived transport carriers.” Cell Mol Life Sci 72(18): 3441-3455.

2014 and Prior

Chi, R.J., Liu, T.T., West, M.C., Wang, J., Odorizzi, G., Burd, C.G., Fission of SNX-BAR-coated endosomal retrograde transport carriers is promoted by the dynamin related protein Vps1. J Cell Biol. Mar 3;204(5):793-806*., 2014

            *Selected as featured article in March Issue Biobytes podcast  

Wu, X, Chi, R.J., Baskin, J.M., Lucast, L., Burd, C.G., De Camilli, P., Reinisch K.M. Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex.Dev Cell. Jan 13;28(1):19-29., 2014

Xu, P, Baldridge, R.D., Chi, R.J., Burd, C.G., Graham, T. Phosphatidylserine flipping enhances membrane curvature and negative charge required for vesicular transport. J Cell Biol. Sep 16;202(6):875-86., 2013

Chi, R. J., Torres, O.T., Segarra V.A, Chang, J., Lansley, T., Newpher, T., Lemmon S. K. Role of Scd5, a protein phosphatase 1 targeting protein, in the phosphoregulation of Sla1 during endocytosis J Cell Sci. Oct. 15; 125(Pt 20): 4728-39., 2012

Boettner,  D.R., Chi, R. J.,Lemmon S. K.  Lessons from yeast for clathrin-mediated endocytosis Nat Cell Biol. Dec 22; 14 (1):2-10., 2011

Collette, J., Chi, R. J., Boettner, D., Linton M. T., Geli, M. I., Mertz, A. J., Lemmon, S.K. Clathrin functions in the absence of terminal domain binding site for adaptor-associated clathrin-box motifs Mol Biol Cell. 14, 3401-13., 2009

Chi, R. J., Simon, A. R., Bienkiewicz, E. A., Felix, A.,  and Keller, T.C., III. Smooth muscle titin Zq domain interaction with the smooth muscle alpha-actinin central rod J Biol Chem. 30, 20959-67., 2008

Chi, R. J. and Keller, T.C., III. Smitin-myosin II coassembly arrays in vitro. In: Cell Biology Protocols, J.Robin Harris, ed., Wiley Press, Hoboken, NJ, pp. 369-371., 2006

Chi, R. J., Olenych, S. G., Kim, K., and Keller, T. C., III. Smooth muscle alpha-actinin interaction with smitin. Int J Biochem. Cell Biol. 37, 1470-1482., 2005

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